{"doi":"10.1128/aem.02261-20","title":"Arsenate-Induced Changes in Bacterial Metabolite and Lipid Pools during Phosphate Stress","abstract":"Arsenic is widespread in the environment and is one of the most ubiquitous environmental pollutants. Parodoxically, the growth of certain bacteria is enhanced by arsenic when phosphate is limited. Arsenate and phosphate are chemically similar, and this behavior is believed to represent a phosphate-sparing phenotype in which arsenate is used in place of phosphate in certain biomolecules. The research presented here uses a global approach to track metabolic changes in an environmentally relevant bacterium during exposure to arsenate when phosphate is low. Our findings are relevant for understanding the environmental fate of arsenic as well as how human-associated microbiomes respond to this common toxin.","journal":"Applied and Environmental Microbiology","year":2020,"id":87184,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":12,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9514,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":344457,"name":"Narayanaganesh Balasubramanian","orcid":"0000-0003-2478-464X","position":1,"is_corresponding":false},{"id":443685,"name":"Lu Wang","orcid":"0000-0003-4979-4895","position":2,"is_corresponding":false},{"id":320288,"name":"Qian Wang","orcid":"0000-0003-4507-0523","position":3,"is_corresponding":false},{"id":437934,"name":"Timothy R. McDermott","orcid":"0000-0001-8293-5106","position":4,"is_corresponding":false},{"id":226468,"name":"Valérie Copié","orcid":"0000-0002-2778-1463","position":5,"is_corresponding":false},{"id":321897,"name":"Gejiao Wang","orcid":null,"position":6,"is_corresponding":false},{"id":316553,"name":"Brian Bothner","orcid":"0000-0003-1295-9609","position":7,"is_corresponding":false},{"id":444557,"name":"Weiping Zhuang","orcid":null,"position":0,"is_corresponding":true}],"reference_count":69,"raw_metadata":null,"created_at":"2026-07-18T21:59:31.247492Z","pmid":"33361371","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}