{"doi":"10.1128/9781555816728.ch138","title":"<i>Isospora, Cyclospora</i>\n, and\n<i>Sarcocystis</i>","abstract":null,"journal":"Manual of Clinical Microbiology","year":2011,"id":603516,"datarank":0.32958368660043297,"base_score":2.1972245773362196,"endowment":2.1972245773362196,"self_citation_contribution":0.32958368660043297,"citation_network_contribution":0.0,"self_endowment_contribution":0.32958368660043297,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":8,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1548158,"name":"Steve J. Upton","orcid":null,"position":1,"is_corresponding":false},{"id":320665,"name":"Louis M. Weiss","orcid":"0000-0002-0357-7396","position":2,"is_corresponding":false},{"id":1548157,"name":"David S. Lindsay","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"<i>Isospora, Cyclospora</i>\n, and\n<i>Sarcocystis</i>","abstract":"The Isospora ( Cystoisospora ), Cyclospora , and Sarcocystis are intestinal coccidia of humans, and oocysts of these coccidia are found in the feces of humans, and diagnosis is based ultimately on demonstrating oocysts ( Isospora or Cyclospora ) or sporocysts (Sarcocystis) in human stool samples. Cyclospora cayetanensis is in the family Eimeriidae, while Sarcocystis hominis and Sarcocystis suihominis are in the family Sarcocystidae. The oocysts are Isospora -like and contain two sporocysts, each with four sporozoites. In areas of endemicity, there is an increased risk of Cyclospora infection with contact with soil and water. Most of the produce items implicated as transmitting Cyclospora are consumed raw, which does not lend itself to prevention by thermal means. Cyclospora species infecting mammals other than humans may also be present in water samples or on produce, and proofs of specificity are needed for these tests designed to look at environmental sources of C. cayetanensis and to detect C. cayetanensis oocysts on produce. Nitazoxanide has been evaluated for activity against C. cayetanensis , and in these studies, its efficacy for the treatment of cyclosporiasis was about 70%. Both I. belli and C. cayetanensis are usually identified by stool examination and are rarely misidentified in human feces. Computer report notes can indicate that trimethoprim-sulfamethoxazole is the drug of choice for treatment of these parasites. PCR can be used for the identification of organisms but is not commercially available and should be indicated as an experimental test.","is_dataset_classified":null,"base_score":2.1972245773362196,"endowment":2.1972245773362196,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"23304386","pmcid":null,"openalex_id":"https://openalex.org/W941293235","authors":[],"funders":[],"total_grants":0,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[{"year":2013,"count":1},{"year":2014,"count":1},{"year":2015,"count":3},{"year":2016,"count":1},{"year":2025,"count":1},{"year":2026,"count":1}],"oa_status":"closed","license":"http://doi.wiley.com/10.1002/tdm_license_1.1","oa_locations":[{"url":"https://onlinelibrary.wiley.com/doi/pdf/10.1128/9781555816728.ch138","host_type":"publisher"},{"url":"https://doi.org/10.1128/9781555816728.ch138","host_type":""}],"fields_of_study":["Parasitic Infections and Diagnostics","Coccidia and coccidiosis research","Toxoplasma gondii Research Studies"],"mesh_terms":[],"keywords":["Cyclospora cayetanensis","Isospora","Cyclospora","Coccidia","Eimeriidae","Sarcocystis","Feces","Biology","Microbiology","Virology","Zoology","Veterinary medicine","Cryptosporidium","Apicomplexa","Parasite hosting","Medicine","Protozoal disease","Immunology"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Clean water and sanitation"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-29T22:08:27.147812Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}