{"doi":"10.1126/science.aav5297","title":"Remembered reward locations restructure entorhinal spatial maps","abstract":"<jats:title>Reward and the map in the brain</jats:title>\n          <jats:p>\n            Recent findings suggest a more complex role of grid cells in the brain than simply coding for space. The grid map in the entorhinal cortex, which is responsible for encoding spatial information, is not as rigid as originally thought and can be distorted by environmental modifications (see the Perspective by Quian Quiroga). Butler\n            <jats:italic>et al.</jats:italic>\n            compared grid cell coding during a free-foraging task and a spatial memory task in rats. They discovered that entorhinal spatial maps restructure to incorporate the location of a learned reward. Boccara\n            <jats:italic>et al.</jats:italic>\n            tested the influence of behaviorally relevant information on the cognitive map that emerges from grid cell firing in the rat medial entorhinal cortex. They found that grid cells participate in neural coding of the goal locality, not the whole environment.\n          </jats:p>\n          <jats:p>\n            <jats:italic>Science</jats:italic>\n            , this issue p.\n            <jats:related-article xmlns:xlink=\"http://www.w3.org/1999/xlink\" ext-link-type=\"doi\" issue=\"6434\" page=\"1447\" related-article-type=\"in-this-issue\" vol=\"363\" xlink:href=\"10.1126/science.aav5297\">1447</jats:related-article>\n            , p.\n            <jats:related-article xmlns:xlink=\"http://www.w3.org/1999/xlink\" ext-link-type=\"doi\" issue=\"6434\" page=\"1443\" related-article-type=\"in-this-issue\" vol=\"363\" xlink:href=\"10.1126/science.aav4837\">1443</jats:related-article>\n            ; see also p.\n            <jats:related-article xmlns:xlink=\"http://www.w3.org/1999/xlink\" ext-link-type=\"doi\" issue=\"6434\" page=\"1388\" related-article-type=\"in-this-issue\" vol=\"363\" xlink:href=\"10.1126/science.aaw8829\">1388</jats:related-article>\n          </jats:p>","journal":"Science","year":2019,"id":682265,"datarank":0.8317766166719345,"base_score":5.545177444479562,"endowment":5.545177444479562,"self_citation_contribution":0.8317766166719345,"citation_network_contribution":0.0,"self_endowment_contribution":0.8317766166719345,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":255,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":649484,"name":"Kiah Hardcastle","orcid":"0000-0002-2337-9290","position":1,"is_corresponding":false},{"id":555941,"name":"Lisa M. Giocomo","orcid":"0000-0003-0416-2528","position":2,"is_corresponding":false},{"id":1467975,"name":"William N. Butler","orcid":"0000-0002-6262-6717","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Remembered reward locations restructure entorhinal spatial maps","abstract":"<jats:title>Reward and the map in the brain</jats:title>\n          <jats:p>\n            Recent findings suggest a more complex role of grid cells in the brain than simply coding for space. The grid map in the entorhinal cortex, which is responsible for encoding spatial information, is not as rigid as originally thought and can be distorted by environmental modifications (see the Perspective by Quian Quiroga). Butler\n            <jats:italic>et al.</jats:italic>\n            compared grid cell coding during a free-foraging task and a spatial memory task in rats. They discovered that entorhinal spatial maps restructure to incorporate the location of a learned reward. Boccara\n            <jats:italic>et al.</jats:italic>\n            tested the influence of behaviorally relevant information on the cognitive map that emerges from grid cell firing in the rat medial entorhinal cortex. They found that grid cells participate in neural coding of the goal locality, not the whole environment.\n          </jats:p>\n          <jats:p>\n            <jats:italic>Science</jats:italic>\n            , this issue p.\n            <jats:related-article xmlns:xlink=\"http://www.w3.org/1999/xlink\" ext-link-type=\"doi\" issue=\"6434\" page=\"1447\" related-article-type=\"in-this-issue\" vol=\"363\" xlink:href=\"10.1126/science.aav5297\">1447</jats:related-article>\n            , p.\n            <jats:related-article xmlns:xlink=\"http://www.w3.org/1999/xlink\" ext-link-type=\"doi\" issue=\"6434\" page=\"1443\" related-article-type=\"in-this-issue\" vol=\"363\" xlink:href=\"10.1126/science.aav4837\">1443</jats:related-article>\n            ; see also p.\n            <jats:related-article xmlns:xlink=\"http://www.w3.org/1999/xlink\" ext-link-type=\"doi\" issue=\"6434\" page=\"1388\" related-article-type=\"in-this-issue\" vol=\"363\" xlink:href=\"10.1126/science.aaw8829\">1388</jats:related-article>\n          </jats:p>","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"30923222","pmcid":"PMC6516752","openalex_id":null,"authors":[],"funders":[{"funder_name":"Office of Naval Research","grant_id":"N000141812690","title":null},{"funder_name":"National Institute of Mental Health","grant_id":"NIMH MH106475","title":null},{"funder_name":"National Institute on Drug Abuse","grant_id":"NIDA DA042012","title":null},{"funder_name":"Stanford University","grant_id":"Interdisciplinary Graduate Fellowship","title":null},{"funder_name":"NIMH NIH HHS","grant_id":"R01 MH106475","title":null},{"funder_name":"NIDA NIH HHS","grant_id":"P50 DA042012","title":null},{"funder_name":"NIMH NIH HHS","grant_id":"R56 MH106475","title":null},{"funder_name":"James S. McDonnell Foundation","grant_id":"","title":null},{"funder_name":"Esther A. and Joseph Klingenstein Fund","grant_id":"","title":null},{"funder_name":"New York Stem Cell Foundation","grant_id":"","title":null}],"total_grants":10,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[],"oa_status":"closed","license":null,"oa_locations":[{"url":"https://syndication.highwire.org/content/doi/10.1126/science.aav5297","host_type":"publisher"},{"url":"https://www.science.org/doi/pdf/10.1126/science.aav5297","host_type":"publisher"}],"fields_of_study":[],"mesh_terms":["Entorhinal Cortex","Animals","Rats","Brain Mapping","Mental Recall","Reward","Head Movements","Male","Spatial Navigation","Grid Cells"],"keywords":[],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[{"name":"doi"}],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-17T19:55:38.282593Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}