{"doi":"10.1126/science.628842","title":"Nonhistone Proteins HMG\n            <sub>1</sub>\n            and HMG\n            <sub>2</sub>\n            Change the DNA Helical Structure","abstract":"<jats:p>\n            Two chromatin nonhistone proteins (from calf thymus) of the high mobility group, HMG\n            <jats:sub>1</jats:sub>\n            and HMG\n            <jats:sub>2</jats:sub>\n            , reduce the linking number (topological winding number) of a circular DNA if the covalent closure of the DNA is carried out in their presence. This indicates that these proteins can either unwind the double helix, or induce a supercoiling of the DNA.\n          </jats:p>","journal":"Science","year":1978,"id":14539,"datarank":15.443840683532445,"base_score":5.5093883366279774,"endowment":5.5093883366279774,"self_citation_contribution":0.8264082504941967,"citation_network_contribution":14.617432433038248,"self_endowment_contribution":0.8264082504941967,"citer_contribution":14.617432433038248,"corpus_percentile":null,"corpus_rank":null,"citation_count":246,"citer_count":200,"citers_with_citation_signal":200,"citers_with_endowment":200,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":114413,"name":"Leroy F. Liu","orcid":null,"position":1,"is_corresponding":false},{"id":114414,"name":"James C. Wang","orcid":null,"position":2,"is_corresponding":false},{"id":114412,"name":"Kashayar Javaherian","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":5.5093883366279774,"endowment":5.5093883366279774,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"628842","pmcid":null,"openalex_id":"https://openalex.org/W2065344667","authors":[],"funders":[],"total_grants":0,"fwci":8.3446,"citation_percentile":0.98506689,"influential_citations":2,"citation_trend":[{"year":2012,"count":2},{"year":2013,"count":8},{"year":2014,"count":5},{"year":2015,"count":12},{"year":2016,"count":8},{"year":2017,"count":8},{"year":2018,"count":4},{"year":2019,"count":3},{"year":2020,"count":6},{"year":2021,"count":5},{"year":2022,"count":8},{"year":2023,"count":3},{"year":2024,"count":4},{"year":2025,"count":1},{"year":2026,"count":1}],"oa_status":"closed","license":null,"oa_locations":[{"url":"https://www.science.org/doi/pdf/10.1126/science.628842","host_type":"publisher"},{"url":"https://doi.org/10.1126/science.628842","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/628842","host_type":"repository"}],"fields_of_study":["DNA and Nucleic Acid Chemistry","RNA and protein synthesis mechanisms","Biology","Medicine","Chemistry","Bacteriophages","Chromosomal Proteins, Non-Histone","DNA, Circular","DNA, Superhelical","DNA, Viral","Nucleic Acid Conformation","Pseudomonas"],"mesh_terms":["Bacteriophages","Chromosomal Proteins, Non-Histone","DNA, Circular","DNA, Superhelical","DNA, Viral","Nucleic Acid Conformation","Pseudomonas"],"keywords":["HMG-CoA reductase","High-mobility group","Non-histone protein","DNA","Chemistry","Biochemistry","Histone","Gene","Enzyme"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-06-01T11:46:44.618071Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}