{"doi":"10.1126/sciadv.abq8566","title":"Robust dynamic brain coactivation states estimated in individuals","abstract":"A confluence of evidence indicates that brain functional connectivity is not static but rather dynamic. Capturing transient network interactions in the individual brain requires a technology that offers sufficient within-subject reliability. Here, we introduce an individualized network-based dynamic analysis technique and demonstrate that it is reliable in detecting subject-specific brain states during both resting state and a cognitively challenging language task. We evaluate the extent to which brain states show hemispheric asymmetries and how various phenotypic factors such as handedness and gender might influence network dynamics, discovering a right-lateralized brain state that occurred more frequently in men than in women and more frequently in right-handed versus left-handed individuals. Longitudinal brain state changes were also shown in 42 patients with subcortical stroke over 6 months. Our approach could quantify subject-specific dynamic brain states and has potential for use in both basic and clinical neuroscience research.","journal":"Science Advances","year":2023,"id":319298,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":56,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.947,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1028038,"name":"Qi Liu","orcid":"0000-0003-4008-2226","position":1,"is_corresponding":false},{"id":341586,"name":"Catherine S. Hubbard","orcid":"0000-0002-9139-2198","position":2,"is_corresponding":false},{"id":341591,"name":"Danhong Wang","orcid":"0000-0001-6780-3033","position":3,"is_corresponding":false},{"id":649728,"name":"Wenzhen Zhu","orcid":"0000-0001-6252-9450","position":4,"is_corresponding":false},{"id":15952,"name":"Michael Fox","orcid":"0000-0001-8848-6399","position":5,"is_corresponding":false},{"id":30835,"name":"Hesheng Liu","orcid":"0000-0002-7233-1509","position":6,"is_corresponding":false},{"id":341588,"name":"Xiaomei Peng","orcid":"0000-0002-4488-9628","position":0,"is_corresponding":true}],"reference_count":87,"raw_metadata":null,"created_at":"2026-07-19T01:07:12.004111Z","pmid":"36652524","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}