{"doi":"10.1118/1.4735661","title":"SU-E-T-572: A Plan Quality Metric for Evaluating Knowledge-Based Treatment Plans","abstract":null,"journal":"Medical Physics","year":2012,"id":682272,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1782438,"name":"J Lo","orcid":null,"position":1,"is_corresponding":false},{"id":30471,"name":"S Das","orcid":"0009-0002-9892-4473","position":2,"is_corresponding":false},{"id":1782437,"name":"V Chanyavanich","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"SU-E-T-572: A Plan Quality Metric for Evaluating Knowledge-Based Treatment Plans","abstract":"PURPOSE: In prostate IMRT treatment planning, the variation in patient anatomy makes it difficult to estimate a priori the potentially achievable extent of dose reduction possible to the rectum and bladder. We developed a mutual information-based framework to estimate the achievable plan quality for a new patient, prior to any treatment planning or optimization. METHODS: The knowledge-base consists of 250 retrospective prostate IMRT plans. Using these prior plans, twenty query cases were each matched with five cases from the database. We propose a simple DVH plan quality metric (PQ) based on the weighted-sum of the areas under the curve (AUC) of the PTV, rectum and bladder. We evaluate the plan quality of knowledge-based generated plans, and established a correlation between the plan quality and case similarity. RESULTS: The introduced plan quality metric correlates well (r2 = 0.8) with the mutual similarity between cases. A matched case with high anatomical similarity can be used to produce a new high quality plan. Not surprisingly, a poorly matched case with low degree of anatomical similarity tends to produce a low quality plan, since the adapted fluences from a dissimilar case cannot be modified sufficiently to yield acceptable PTV coverage. CONCLUSIONS: The plan quality metric is well-correlated to the degree of anatomical similarity between a new query case and matched cases. Further work will investigate how to apply this metric to further stratify and select cases for knowledge-based planning.","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"28517094","pmcid":null,"openalex_id":"https://openalex.org/W2062335211","authors":[],"funders":[],"total_grants":0,"fwci":0.0,"citation_percentile":0.11420605,"influential_citations":0,"citation_trend":[],"oa_status":"closed","license":"http://doi.wiley.com/10.1002/tdm_license_1","oa_locations":[{"url":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1118%2F1.4735661","host_type":"publisher"},{"url":"http://onlinelibrary.wiley.com/wol1/doi/10.1118/1.4735661/fullpdf","host_type":"publisher"},{"url":"https://doi.org/10.1118/1.4735661","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/28517094","host_type":"repository"}],"fields_of_study":["Machine Learning in Healthcare","Data Management and Algorithms","Advanced Radiotherapy Techniques"],"mesh_terms":[],"keywords":["Metric (unit)","Similarity (geometry)","Plan (archaeology)","Computer science","Quality (philosophy)","Radiation treatment planning","Data mining","A priori and a posteriori","Artificial intelligence","Medical physics","Mathematics","Medicine","Radiology","Image (mathematics)","Operations management","Radiation therapy","Geography","Anatomy","Databases","Intensity modulated radiation therapy","Quasicrystals","Medical Treatment Planning"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-17T19:55:47.301997Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}