{"doi":"10.1117/12.3003007.short","title":"Exploring optoretinographic responses of photoreceptor function in disease-affected retinas","abstract":"Assessment of the functional response of photoreceptors plays an important role in assessing and treating vision loss. Optoretinography (ORG) is an emerging non-invasive technique that measures the photoreceptors’ functional response to external light stimuli using optical coherence tomography (OCT) or other phase-sensitive imaging modalities. Recently a novel velocity-based ORG method was demonstrated, illustrating the feasibility of measuring photoreceptor function with clinical-grade OCT systems. Here we test this technique on diseaseaffected retinae of human subjects. The disease-affected retinae exhibited altered responses when compared to a healthy volunteer. The findings indicate promise for this novel tool to find applications in the clinic and clinical research. <br>","journal":"UTUPub (University of Turku)","year":2025,"id":587965,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9579,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1504275,"name":"Langlo Christopher S.","orcid":null,"position":1,"is_corresponding":false},{"id":1504276,"name":"Vienola Kari V.","orcid":null,"position":2,"is_corresponding":false},{"id":1504277,"name":"Bartuzel Maciej M.","orcid":null,"position":3,"is_corresponding":false},{"id":1504278,"name":"Pijewska Ewelina","orcid":null,"position":4,"is_corresponding":false},{"id":1504279,"name":"Zawadzki Robert J.","orcid":null,"position":5,"is_corresponding":false},{"id":1504280,"name":"Jonnal Ravi S.","orcid":null,"position":6,"is_corresponding":false},{"id":1504274,"name":"Maddipatla Reddikumar","orcid":null,"position":0,"is_corresponding":true}],"reference_count":0,"raw_metadata":null,"created_at":"2026-07-19T02:59:43.096742Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}