{"doi":"10.1115/sbc2010-19233","title":"Stress Concentrations of Vulnerable Plaques With a Composite Variable Core","abstract":"<jats:p>Vulnerable plaques are inflamed, active, and growing lesions which are prone to complications such as rupture, luminal and mural thrombosis, intraplaque hemorrhage, and rapid progression to stenosis. It remains difficult to assess what factors influence the biomechanical stability of vulnerable plaques and promote some of them to rupture while others remain intact. The rupture of thin fibrous cap overlying the necrotic core of a vulnerable plaque is the principal cause of acute coronary syndrome. The mechanism or mechanisms responsible for the sudden conversion of a stable atherosclerotic plaque to a life threatening athero-thrombotic lesion are not fully understood. It has been widely assumed that plaque morphology is the major determinant of clinical outcome [1, 2]. Thin-cap fibroatheroma with a large necrotic core and a fibrous cap of &lt; 65μm was describes as a more specific precursor of plaque rupture due to tissue stress.</jats:p>","journal":"ASME 2010 Summer Bioengineering Conference, Parts A and B","year":2010,"id":633463,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1642439,"name":"Aronis Ze’ev","orcid":null,"position":1,"is_corresponding":false},{"id":1642440,"name":"Rami Eliasy","orcid":null,"position":2,"is_corresponding":false},{"id":1516822,"name":"Rami Haj-Ali","orcid":null,"position":3,"is_corresponding":false},{"id":1642443,"name":"Shmuel Einav","orcid":null,"position":4,"is_corresponding":false},{"id":1642438,"name":"Eyass Massarwa","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Stress Concentrations of Vulnerable Plaques With a Composite Variable Core","abstract":"<jats:p>Vulnerable plaques are inflamed, active, and growing lesions which are prone to complications such as rupture, luminal and mural thrombosis, intraplaque hemorrhage, and rapid progression to stenosis. It remains difficult to assess what factors influence the biomechanical stability of vulnerable plaques and promote some of them to rupture while others remain intact. The rupture of thin fibrous cap overlying the necrotic core of a vulnerable plaque is the principal cause of acute coronary syndrome. The mechanism or mechanisms responsible for the sudden conversion of a stable atherosclerotic plaque to a life threatening athero-thrombotic lesion are not fully understood. It has been widely assumed that plaque morphology is the major determinant of clinical outcome [1, 2]. Thin-cap fibroatheroma with a large necrotic core and a fibrous cap of &lt; 65μm was describes as a more specific precursor of plaque rupture due to tissue stress.</jats:p>","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"19767382","pmcid":null,"openalex_id":"https://openalex.org/W1985279168","authors":[],"funders":[],"total_grants":0,"fwci":0.0,"citation_percentile":0.08939849,"influential_citations":0,"citation_trend":[],"oa_status":"closed","license":null,"oa_locations":[{"url":"http://asmedigitalcollection.asme.org/SBC/proceedings-pdf/doi/10.1115/SBC2010-19233/4200892/29_1.pdf","host_type":"publisher"},{"url":"https://doi.org/10.1115/sbc2010-19233","host_type":"conference"},{"url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1030.5","host_type":""}],"fields_of_study":["Elasticity and Material Modeling","Cell Adhesion Molecules Research","Coronary Interventions and Diagnostics","Medicine"],"mesh_terms":[],"keywords":["Fibrous cap","Vulnerable plaque","Medicine","Thrombosis","Lesion","Stenosis","Acute coronary syndrome","Core (optical fiber)","Cardiology","Pathology","Internal medicine","Materials science","Myocardial infarction"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-06T12:07:48.958477Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}