{"doi":"10.1111/tid.12126","title":"<scp>E</scp>pstein–<scp>B</scp>arr virus‐associated smooth muscle tumors in a composite tissue allograft and a pediatric liver transplant recipient","abstract":"<jats:title>Abstract</jats:title><jats:p><jats:styled-content style=\"fixed-case\">E</jats:styled-content>pstein–<jats:styled-content style=\"fixed-case\">B</jats:styled-content>arr virus (<jats:styled-content style=\"fixed-case\">EBV</jats:styled-content>) is known to establish latent infections in B‐lymphocytes that can cause lymphoproliferative disorders particularly in immunocompromised patients. More recently, the development of rare <jats:styled-content style=\"fixed-case\">EBV</jats:styled-content>‐associated smooth muscle tumors has been reported in transplant recipients. We herein describe 2 new cases of <jats:styled-content style=\"fixed-case\">EBV</jats:styled-content>‐associated post‐transplant smooth muscle tumors (<jats:styled-content style=\"fixed-case\">EBV</jats:styled-content>‐<jats:styled-content style=\"fixed-case\">PTSMT</jats:styled-content>), including the first in a facial composite tissue graft recipient. Among the striking features shared by these 2 patients were their young ages, the fact that they were naïve for <jats:styled-content style=\"fixed-case\">EBV</jats:styled-content> before the transplantation, that they developed a post‐transplant lymphoproliferative disorder before the diagnosis of <jats:styled-content style=\"fixed-case\">EBV</jats:styled-content>‐<jats:styled-content style=\"fixed-case\">PTSMT</jats:styled-content>, and that they responded favorably to reduction of immunosuppression. Radiological and histologic features of <jats:styled-content style=\"fixed-case\">EBV</jats:styled-content>‐<jats:styled-content style=\"fixed-case\">PTSMT</jats:styled-content> are shown. Finally, pathophysiology and therapeutic management of <jats:styled-content style=\"fixed-case\">EBV</jats:styled-content>‐<jats:styled-content style=\"fixed-case\">PTSMT</jats:styled-content> are discussed based on a comprehensive review of the literature.</jats:p>","journal":"Transplant Infectious Disease","year":2013,"id":38373,"datarank":1.3584647566424184,"base_score":3.295836866004329,"endowment":3.295836866004329,"self_citation_contribution":0.4943755299006494,"citation_network_contribution":0.864089226741769,"self_endowment_contribution":0.4943755299006494,"citer_contribution":0.864089226741769,"corpus_percentile":null,"corpus_rank":null,"citation_count":26,"citer_count":21,"citers_with_citation_signal":19,"citers_with_endowment":19,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":190423,"name":"A.‐S. Brunet","orcid":null,"position":1,"is_corresponding":false},{"id":190424,"name":"V. Hervieu","orcid":null,"position":2,"is_corresponding":false},{"id":190425,"name":"C. Chauvet","orcid":null,"position":3,"is_corresponding":false},{"id":190426,"name":"F. Buron","orcid":null,"position":4,"is_corresponding":false},{"id":190427,"name":"S. Collardeau‐Frachon","orcid":null,"position":5,"is_corresponding":false},{"id":190428,"name":"C. Rivet","orcid":null,"position":6,"is_corresponding":false},{"id":190429,"name":"P. Cassier","orcid":null,"position":7,"is_corresponding":false},{"id":190430,"name":"S. Testelin","orcid":null,"position":8,"is_corresponding":false},{"id":190431,"name":"A. Lachaux","orcid":null,"position":9,"is_corresponding":false},{"id":190432,"name":"E. Morelon","orcid":null,"position":10,"is_corresponding":false},{"id":190433,"name":"O. Thaunat","orcid":null,"position":11,"is_corresponding":false},{"id":190422,"name":"A. Conrad","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":3.295836866004329,"endowment":3.295836866004329,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"24034213","pmcid":null,"openalex_id":"https://openalex.org/W2008223653","authors":[],"funders":[],"total_grants":0,"fwci":1.2664,"citation_percentile":0.7938794,"influential_citations":1,"citation_trend":[{"year":2014,"count":1},{"year":2015,"count":5},{"year":2016,"count":2},{"year":2018,"count":3},{"year":2019,"count":4},{"year":2020,"count":1},{"year":2021,"count":5},{"year":2022,"count":2},{"year":2023,"count":1},{"year":2025,"count":1},{"year":2026,"count":1}],"oa_status":"closed","license":"http://onlinelibrary.wiley.com/termsAndConditions#vor","oa_locations":[{"url":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Ftid.12126","host_type":"publisher"},{"url":"https://onlinelibrary.wiley.com/doi/pdf/10.1111/tid.12126","host_type":"publisher"},{"url":"https://doi.org/10.1111/tid.12126","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/24034213","host_type":"repository"}],"fields_of_study":["Viral-associated cancers and disorders","Histiocytic Disorders and Treatments","Parvovirus B19 Infection Studies","Medicine","Adult","Allografts","Epstein-Barr Virus Infections","Facial Transplantation","Female","Herpesvirus 4, Human","Humans","Immunocompromised Host","Immunosuppression Therapy","Infant","Liver Transplantation","Lymphoma, B-Cell","Male","Postoperative Complications","Smooth Muscle Tumor"],"mesh_terms":["Adult","Herpesvirus 4, Human","Female","Humans","Immunosuppression Therapy","Infant","Male","Postoperative Complications","Liver Transplantation","Lymphoma, B-Cell","Immunocompromised Host","Smooth Muscle Tumor","Epstein-Barr Virus Infections","Facial Transplantation","Allografts"],"keywords":["Medicine","Immunosuppression","Lymphoproliferative disorders","Virus","Epstein–Barr virus","Post-transplant lymphoproliferative disorder","Transplantation","Immunology","Pathophysiology","Pathology","Lymphoma","Internal medicine","Epstein-Barr virus","Composite Tissue Allotransplantation","Ptld","Post-transplant Lymphoproliferative Disorders","Face Transplantation","Post-transplant Smooth Muscle Tumors"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-06-11T02:50:12.019904Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}