{"doi":"10.1111/pce.14596","title":"The integration of reactive oxygen species (ROS) and calcium signalling in abiotic stress responses","abstract":"<jats:title>Abstract</jats:title><jats:p>Reactive oxygen species (ROS) and calcium (Ca<jats:sup>2+</jats:sup>) signalling are interconnected in the perception and transmission of environmental signals that control plant growth, development and defence. The concept that systemically propagating Ca<jats:sup>2+</jats:sup> and ROS waves function together with electric signals in directional cell‐to‐cell systemic signalling and even plant‐to‐plant communication, is now firmly imbedded in the literature. However, relatively few mechanistic details are available regarding the management of ROS and Ca<jats:sup>2+</jats:sup> signals at the molecular level, or how synchronous and independent signalling might be achieved in different cellular compartments. This review discusses the proteins that may serve as nodes or connecting bridges between the different pathways during abiotic stress responses, highlighting the crosstalk between ROS and Ca<jats:sup>2+</jats:sup> pathways in cell signalling. We consider putative molecular switches that connect these signalling pathways and the molecular machinery that achieves the synergistic operation of ROS and Ca<jats:sup>2+</jats:sup> signals.</jats:p>","journal":"Plant, Cell &amp; Environment","year":2023,"id":29907,"datarank":3.426197551643826,"base_score":5.476463551931511,"endowment":5.476463551931511,"self_citation_contribution":0.8214695327897268,"citation_network_contribution":2.6047280188540993,"self_endowment_contribution":0.8214695327897268,"citer_contribution":2.6047280188540993,"corpus_percentile":null,"corpus_rank":null,"citation_count":238,"citer_count":200,"citers_with_citation_signal":141,"citers_with_endowment":141,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":163747,"name":"Christine H. Foyer","orcid":"0000-0001-5989-6989","position":1,"is_corresponding":false},{"id":163748,"name":"Girdhar K. Pandey","orcid":"0000-0001-9180-0924","position":2,"is_corresponding":false},{"id":163746,"name":"Barkha Ravi","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":5.459585514144159,"endowment":5.459585514144159,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"37132157","pmcid":null,"openalex_id":"https://openalex.org/W4367835058","authors":[],"funders":[{"funder_name":"Department of Biotechnology, Government of West Bengal","grant_id":"","title":null}],"total_grants":1,"fwci":86.2341,"citation_percentile":0.99973689,"influential_citations":2,"citation_trend":[{"year":2023,"count":15},{"year":2024,"count":57},{"year":2025,"count":94},{"year":2026,"count":68}],"oa_status":"hybrid","license":"cc-by-nc","oa_locations":[{"url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/pce.14596","host_type":"journal"},{"url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/pce.14596","host_type":"HYBRID"},{"url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/pce.14596","host_type":"publisher"},{"url":"https://onlinelibrary.wiley.com/doi/pdf/10.1111/pce.14596","host_type":"publisher"},{"url":"https://doi.org/10.1111/pce.14596","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/37132157","host_type":"repository"},{"url":"https://research.birmingham.ac.uk/en/publications/2102d612-8d96-4c9c-8f1b-9d039dff962a","host_type":"repository"},{"url":"https://pure-oai.bham.ac.uk/ws/files/192680963/pce.14596.pdf","host_type":"repository"}],"fields_of_study":["Plant and Biological Electrophysiology Studies","Plant Stress Responses and Tolerance","Plant Parasitism and Resistance","Medicine","Environmental Science","Biology","Reactive Oxygen Species","Calcium","Plants","Stress, Physiological","Signal Transduction"],"mesh_terms":["Calcium","Plants","Stress, Physiological","Signal Transduction","Reactive Oxygen Species"],"keywords":["Crosstalk","Signalling","Reactive oxygen species","Signalling pathways","Calcium signaling","Cell biology","Abiotic component","Calcium","Signal transduction","Biology","Cell signaling","Chemistry","Ecology","Physics","Calcium Sensor Proteins"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Life in Land"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-06-09T01:09:06.457209Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}