{"doi":"10.1111/jocd.16744","title":"Relationships Between Quality of Life and Emotional Resilience for Those With and Without Acne","abstract":"Although not life-threatening or physically debilitating, acne vulgaris has a greater psychological impact than many other chronic conditions [1]. Compared with patients with asthma, epilepsy, back pain, arthritis, or psoriasis, patients with acne experience similar, if not greater, impairment in mental health scores [1]. Resilience helps maintain mental health in vulnerable populations undergoing stressors [2]. Despite extensive research on mental health and acne, there is a notable lack of data exploring the connection between skin-related quality of life (SRQL) and emotional resilience in patients with acne. Resilience, the ability to adapt to stress and adversity [2], is essential for maintaining mental health. Emotional resilience can mitigate the psychological impact of stressors, leading to better mental health outcomes and improved satisfaction with clinical care [2]. This exploratory study aimed to address how emotional resilience, measured using the Connor–Davidson Resilience Scale (CD-RISC), correlates with SRQL, measured using the Skindex-16, in patients with acne versus acne-free controls. The Skindex-16 is a validated patient-reported outcome measure that assesses the effects of skin disease on quality of life across three domains: physical symptoms like itching and irritation, emotional responses such as worry or embarrassment, and functional impacts including difficulties with social interactions and work [3]. We used data from a previously published project on acne and lifestyle among adolescents and young adults [4]. Individuals between the ages of 12 and 24 years, with and without acne were included. Controls were excluded if they ever used isotretinoin and/or if they had a chronic inflammatory skin disease flaring at their dermatology visit. For both cases and controls, female participants could not be pregnant or breastfeeding or ever have been diagnosed with polycystic ovary syndrome. Only participants with complete data were included, resulting in a sample of 195 participants, with an average age of 18.7 years and ranging from 12 to 24 years. Most participants were female (n = 120 [61.5%]) and non-Hispanic White (n = 159 [81.5%]) (Table 1). Most participants had left secondary education and were attending college or trade school after high school (n = 76 [39.0%]), were attending graduate school (n = 11 [5.6%]), or had left school entirely (n = 27 [13.8%]). The rest were in middle school (n = 24 [12.3%]) or high school (n = 57 [29.2%]). Forty-seven (24.1%) had full-time employment, 68 (34.9%) worked part-time jobs, and 2 (1.0%) had both full-time and part-time jobs. Among acne cases, severity ranged from almost clear to severe. Skindex-16 instructions (but not questions) were modified to ask participants to reflect specifically on their acne or other skin condition. Continuous and categorical variables were assessed using Student's t-tests and chi-squared tests, respectively. Spearman's rank correlation was used to assess the relationship between emotional resilience and SRQL variables. An α < 0.05 was considered statistically significant. Stata version 16.1 was used for analyses. The mean (± standard deviation) emotional resilience score was 69.9 (± 14.4). Mean scores for Skindex-16 symptoms, emotions, and functioning domains were 18.0 (± 19.0), 35.5 (± 30.5), and 12.3 (± 19.1), respectively. All three domains had negative correlations with emotional resilience: symptoms (ρ = −0.15, p = 0.04), emotions (ρ = −0.26, p < 0.01), and functioning (ρ = −0.29, p < 0.01), indicating that greater emotional resilience correlated with improved SRQL. When assessing values by acne cases versus acne-free controls, emotions and functioning had significant negative correlations with emotional resilience among cases while symptoms had a significant negative correlation with emotional resilience among controls (Table 2). These findings suggest that while symptoms are significantly related to SRQL in acne-free individuals, ","journal":"Journal of Cosmetic Dermatology","year":2025,"id":551054,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9514,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1320835,"name":"Nicole Ufkes","orcid":"0009-0000-7308-213X","position":1,"is_corresponding":false},{"id":532044,"name":"Aaron M. Secrest","orcid":"0000-0001-9297-0941","position":2,"is_corresponding":false},{"id":727214,"name":"Maureen A. Murtaugh","orcid":"0000-0001-5281-0302","position":3,"is_corresponding":false},{"id":479565,"name":"Megan E. Vanneman","orcid":"0000-0003-3013-1362","position":4,"is_corresponding":false},{"id":1320834,"name":"Ashley Snyder","orcid":"0000-0002-1980-2092","position":5,"is_corresponding":false},{"id":1214374,"name":"Caroline J. Stone","orcid":"0000-0002-1697-1659","position":0,"is_corresponding":true}],"reference_count":5,"raw_metadata":null,"created_at":"2026-07-19T02:54:20.915388Z","pmid":"39760180","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}