{"doi":"10.1111/jgs.19379","title":"Aligning Medications With What Matters Most: Conversations Between Pharmacists, People With Dementia, and Care Partners","abstract":"INTRODUCTION: Successful deprescribing for people with dementia (PWD) depends on communication about medication-related priorities between PWD, care partners and clinicians. The objective of this study was to gain in-depth knowledge of how elicitation of PWD and care partner medication-related priorities during a deprescribing intervention shaped discussions with pharmacists about medications. METHODS: Qualitative analysis of audio-recorded interactions between pharmacists and patient-care partner dyads in a pilot study of a pharmacist-led deprescribing intervention for PWD in primary care. Patients ≥ 65 years taking ≥ 7 medications and care partners were recruited from an integrated delivery system in Colorado and a community-based medical practice in Maryland. Qualitative content analysis was used to analyze 82 transcripts from encounters with 55 patient-care partner dyads. RESULTS: The mean (SD) age of PWD was 81 (8.1) years; 45% were women, 33% Black, and 15% Hispanic. PWD took an average of 13 (±5.3) medications at baseline. Care partners were on average 66 (13) years of age and most were spouses/partners of the PWD. Content analysis identified five themes: (1) Reducing medication-related treatment burden; (2) Alleviating burdensome symptoms; (3) Maintaining cognition and function; (4) Discussion of tradeoffs; (5) Challenges to deprescribing. After eliciting patient and care partner priorities, pharmacists recommended both deprescribing and prescribing. CONCLUSION: Findings from this secondary analysis of a pilot deprescribing intervention suggest eliciting medication-related priorities of PWD and care partners can support goal-concordant care. These results can inform development of interventions to optimize medications for this population.","journal":"Journal of the American Geriatrics Society","year":2025,"id":530346,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":5,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9553,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1221487,"name":"Rosalphie Quiles","orcid":"0009-0009-0896-107X","position":1,"is_corresponding":false},{"id":1221488,"name":"Andrea E. Daddato","orcid":"0000-0001-6421-4217","position":2,"is_corresponding":false},{"id":868996,"name":"Aleksandra Wec","orcid":"0000-0001-6382-3678","position":3,"is_corresponding":false},{"id":1221489,"name":"Kathy Gleason","orcid":"0000-0002-0487-9871","position":4,"is_corresponding":false},{"id":1410412,"name":"Tobie Taylor McPhail","orcid":null,"position":5,"is_corresponding":false},{"id":1222153,"name":"Jessica Merrey","orcid":null,"position":6,"is_corresponding":false},{"id":1222154,"name":"Linda A. Weffald","orcid":null,"position":7,"is_corresponding":false},{"id":1222155,"name":"Meghan Swarthout","orcid":null,"position":8,"is_corresponding":false},{"id":1222156,"name":"Scott Feeser","orcid":null,"position":9,"is_corresponding":false},{"id":270278,"name":"Cynthia M. Boyd","orcid":"0000-0001-5642-9015","position":10,"is_corresponding":false},{"id":353462,"name":"Jennifer L. Wolff","orcid":"0000-0002-7898-3903","position":11,"is_corresponding":false},{"id":320228,"name":"Marcela D. Blinka","orcid":"0000-0003-0369-9331","position":12,"is_corresponding":false},{"id":251910,"name":"Elizabeth A. Bayliss","orcid":"0000-0002-5264-0670","position":13,"is_corresponding":false},{"id":491985,"name":"Rebecca S. Boxer","orcid":"0000-0002-3715-616X","position":14,"is_corresponding":false},{"id":732736,"name":"Ariel R. Green","orcid":"0000-0003-4127-4617","position":0,"is_corresponding":true}],"reference_count":28,"raw_metadata":null,"created_at":"2026-07-19T02:51:05.836974Z","pmid":"39898453","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}