{"doi":"10.1111/jgs.18870","title":"Willingness to take less medication for type 2 diabetes among older patients: The Diabetes &amp; Aging Study","abstract":"BACKGROUND: To examine the willingness of older patients to take less diabetes medication (de-intensify) and to identify characteristics associated with willingness to de-intensify treatment. METHODS: Survey conducted in 2019 in an age-stratified, random sample of older (65-100 years) adults with diabetes on glucose-lowering medications in the Kaiser Permanente Northern California Diabetes Registry. We classified survey responses to the question: \"I would be willing to take less medication for my diabetes\" as willing, neutral, or unwilling to de-intensify. Willingness to de-intensify treatment was examined by several clinical characteristics, including American Diabetes Association (ADA) health status categories used for individualizing glycemic targets. Analyses were weighted to account for over-sampling of older individuals. RESULTS: A total of 1337 older adults on glucose-lowering medication(s) were included (age 74.2 ± 6.0 years, 44% female, 54.4% non-Hispanic white). The proportions of participants willing, neutral, or unwilling to take less medication were 51.2%, 27.3%, and 21.5%, respectively. Proportions of willing to take less medication varied by age (65-74 years: 54.2% vs. 85+ years: 38.5%) and duration of diabetes (0-4 years: 61.0% vs. 15+ years: 44.2%), both p < 0.001. Patients on 1-2 medications were more willing to take less medication(s) compared with patients on 10+ medications (62.1% vs. 46.6%, p = 0.03). Similar proportions of willingness to take less medications were seen across ADA health status, and HbA1c. Willingness to take less medication(s) was similar across survey responses to questions about patient-clinician relationships. CONCLUSIONS: Clinical guidelines suggest considering treatment de-intensification in older patients with longer duration of diabetes, yet patients with these characteristics are less likely to be willing to take less medication(s).","journal":"Journal of the American Geriatrics Society","year":2024,"id":465043,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":4,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.7568,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":630328,"name":"Melissa M. Parker","orcid":"0000-0002-0113-5041","position":1,"is_corresponding":false},{"id":271500,"name":"Elbert S. Huang","orcid":"0000-0002-4628-2061","position":2,"is_corresponding":false},{"id":251907,"name":"Richard W. Grant","orcid":"0000-0002-6164-8025","position":3,"is_corresponding":false},{"id":360987,"name":"Howard H. Moffet","orcid":"0000-0002-8728-774X","position":4,"is_corresponding":false},{"id":677060,"name":"Neda Laiteerapong","orcid":"0000-0003-0124-4325","position":5,"is_corresponding":false},{"id":1296201,"name":"Rajesh Jain","orcid":"0000-0003-3521-284X","position":6,"is_corresponding":false},{"id":360986,"name":"Jennifer Y. Liu","orcid":"0000-0002-9702-7415","position":7,"is_corresponding":false},{"id":329035,"name":"Kasia J. Lipska","orcid":"0000-0002-0348-742X","position":8,"is_corresponding":false},{"id":360981,"name":"Andrew J. Karter","orcid":"0000-0001-5527-316X","position":9,"is_corresponding":false},{"id":1290837,"name":"Shanzay Haider","orcid":"0000-0001-9195-3517","position":0,"is_corresponding":true}],"reference_count":24,"raw_metadata":null,"created_at":"2026-07-19T02:04:46.201722Z","pmid":"38471959","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}