{"doi":"10.1111/jdv.16325","title":"Mycosis fungoides: developments in incidence, treatment and survival","abstract":"BACKGROUND: Prior studies have demonstrated improved disease-specific survival of mycosis fungoides (MF) patients over the last 50 years. OBJECTIVE: To analyse patterns of survival and incidence from 1973 to 2016 and determine whether apparent improvements in MF-specific survival are due to lead-time bias rather than improvements in treatment. METHODS: We performed an analysis of 10 155 patients diagnosed with MF from 1973 to 2016 in the United States cancer registries of SEER-18. We also performed a literature review of papers including stage data for unselected populations of MF patients prior to 2000. RESULTS: Incidence of MF increased from 3.0 per million person-years in the 1970s to 5.9 in the 2010s. For all cohorts, non-Hodgkin lymphoma (including MF) was the leading cause of death. Survival analysis demonstrated marked improvement in disease-specific and overall survival from the 1970s to 2010s. Based on systematic review of the literature, 32%-73% of patients diagnosed prior to 2000 were diagnosed with early-stage disease, as opposed to 81% of patients in the SEER 2000-2016 cohort (P < 0.035 for all cohorts). CONCLUSIONS: Although there have been improvements in MF-related survival over the last 50 years, these may reflect improvements in our ability to diagnose early-stage disease rather than improved treatment.","journal":"Journal of the European Academy of Dermatology and Venereology","year":2020,"id":67266,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":47,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.868,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":356302,"name":"Krishnan R. Patel","orcid":"0000-0003-2120-1939","position":1,"is_corresponding":false},{"id":357543,"name":"Kavita Goyal","orcid":null,"position":2,"is_corresponding":false},{"id":356303,"name":"Daniel E. O’Leary","orcid":"0000-0002-5240-9516","position":3,"is_corresponding":false},{"id":334865,"name":"Nathan Rubin","orcid":"0000-0001-7162-5225","position":4,"is_corresponding":false},{"id":356304,"name":"David R. Pearson","orcid":"0000-0001-8503-5293","position":5,"is_corresponding":false},{"id":357544,"name":"Kimberly Bohjanen","orcid":null,"position":6,"is_corresponding":false},{"id":356305,"name":"Amrita Goyal","orcid":"0000-0003-3790-8242","position":7,"is_corresponding":false},{"id":357542,"name":"A. Kaufman","orcid":null,"position":0,"is_corresponding":true}],"reference_count":38,"raw_metadata":null,"created_at":"2026-07-18T21:15:12.020735Z","pmid":"32141115","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}