{"doi":"10.1111/jcpp.13738","title":"Emotional dysregulation in childhood and disordered eating and self‐harm in adolescence: prospective associations and mediating pathways","abstract":"BACKGROUND: Emotional dysregulation may be a risk factor for disordered eating and self-harm in young people, but few prospective studies have assessed these associations long-term, or considered potential mediators. We examined prospective relationships between childhood emotional dysregulation and disordered eating and self-harm in adolescence; and social cognition, emotional recognition, and being bullied as mediators. METHODS: We analysed Avon Longitudinal Study of Parents and Children data on 3,453 males and 3,481 females. We examined associations between emotional dysregulation at 7 years and any disordered eating and any self-harm at 16 years with probit regression models. We also assessed whether social cognition (7 years), emotional recognition (8 years) and bullying victimisation (11 years) mediated these relationships. RESULTS: Emotional dysregulation at age 7 years was associated with disordered eating [fully adjusted probit B (95% CI) = 0.082 (0.029, 0.134)] and self-harm [fully adjusted probit B (95% CI) = 0.093 (0.036, 0.150)] at age 16 years. There was no evidence of sex interactions or difference in effects between self-harm and disordered eating. Mediation models found social cognition was a key pathway to disordered eating (females 51.2%; males 27.0% of total effect) and self-harm (females 15.7%; males 10.8% of total effect). Bullying victimisation was an important pathway to disordered eating (females 17.1%; males 10.0% of total effect), but only to self-harm in females (15.7% of total effect). Indirect effects were stronger for disordered eating than self-harm. CONCLUSIONS: In males and females, emotional dysregulation in early childhood is associated with disordered eating and self-harm in adolescence and may be a useful target for prevention and treatment. Mediating pathways appeared to differ by sex and outcome, but social cognition was a key mediating pathway for both disordered eating and self-harm.","journal":"Journal of Child Psychology and Psychiatry","year":2022,"id":244488,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":29,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9545,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":93778,"name":"Jon Heron","orcid":"0000-0001-6199-5644","position":1,"is_corresponding":false},{"id":337459,"name":"Becky Mars","orcid":"0000-0002-8132-6920","position":2,"is_corresponding":false},{"id":416663,"name":"Francesca Solmi","orcid":"0000-0003-0219-9503","position":3,"is_corresponding":false},{"id":337460,"name":"Lucy Biddle","orcid":"0000-0002-1090-8771","position":4,"is_corresponding":false},{"id":23072,"name":"David Gunnell","orcid":"0000-0002-0829-6470","position":5,"is_corresponding":false},{"id":570732,"name":"Gemma Hammerton","orcid":"0000-0002-7781-3857","position":6,"is_corresponding":false},{"id":105675,"name":"Paul Moran","orcid":"0000-0002-9257-8699","position":7,"is_corresponding":false},{"id":6136,"name":"Marcus Robert Munafo","orcid":"0000-0002-4049-993X","position":8,"is_corresponding":false},{"id":684542,"name":"Ian S. Penton‐Voak","orcid":"0000-0003-4232-0953","position":9,"is_corresponding":false},{"id":570859,"name":"Andy Skinner","orcid":"0000-0001-7019-163X","position":10,"is_corresponding":false},{"id":570858,"name":"Anne Stewart","orcid":"0000-0001-6560-2553","position":11,"is_corresponding":false},{"id":570860,"name":"Helen Bould","orcid":"0000-0001-8163-3210","position":12,"is_corresponding":false},{"id":570857,"name":"Naomi Warne","orcid":"0000-0001-6160-8982","position":0,"is_corresponding":true}],"reference_count":65,"raw_metadata":null,"created_at":"2026-07-19T00:23:30.364338Z","pmid":"36541428","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}