{"doi":"10.1111/jcpe.70087","title":"Outcomes of Active Periodontal Therapy in a Specialist University Setting Following\n                    <scp>EFP S3</scp>\n                    Treatment Guideline in Stage III–IV Periodontitis Patients","abstract":"<jats:title>ABSTRACT</jats:title>\n                  <jats:sec>\n                    <jats:title>Aim</jats:title>\n                    <jats:p>To describe the efficacy of steps I–II–III of periodontal therapy performed in a specialist university setting following EFP S3 treatment guideline and to assess factors associated with the achievement of endpoints of therapy (EoT).</jats:p>\n                  </jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods</jats:title>\n                    <jats:p>Records of 131 stage III–IV periodontitis patients were collected retrospectively. Residual pockets (probing pocket depth [PPD] 5 mm with bleeding on probing [BoP] or PPD ≥ 6 mm) after steps I–II (T1) received repeated subgingival instrumentation (RSI) or surgery and were re‐evaluated after 1 year (T2). EoT (no PPD ≥ 5 mm BoP+ and no PPD ≥ 6 mm) rate at T1 and T2 was computed, and predictors explored through multilevel analyses.</jats:p>\n                  </jats:sec>\n                  <jats:sec>\n                    <jats:title>Results</jats:title>\n                    <jats:p>At T1, EoT was 67.8%, with step III yielding an additional 90.0% of EoT in PPD = 5 mm BoP+ and 85.3% in PPD ≥ 6 mm. Factors negatively associated with EoT were: posterior teeth, furcation involvement (degree II–III), initial PPD, interproximal location and plaque. When considering only pockets ≥ 6 mm, factors were PPD at T1, type of intervention (resective surgery over RSI) and plaque at T2. Overall, 55.7% of patients reached EoT, 16.1% achieved ‘stable periodontitis’ (PPD ≤ 4 mm, no PPD = 4 mm BoP+, BoP &lt; 10%).</jats:p>\n                  </jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions</jats:title>\n                    <jats:p>Guideline‐based periodontal therapy achieved EoT targets in 93.3% of sites and 50% of patients with Stage III–IV periodontitis.</jats:p>\n                  </jats:sec>","journal":"Journal of Clinical Periodontology","year":2026,"id":597806,"datarank":0.16479184330021646,"base_score":1.0986122886681096,"endowment":1.0986122886681096,"self_citation_contribution":0.16479184330021646,"citation_network_contribution":0.0,"self_endowment_contribution":0.16479184330021646,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1531569,"name":"Federica Romano","orcid":"0000-0002-5172-299X","position":1,"is_corresponding":false},{"id":1531570,"name":"Luigi Costanzo","orcid":null,"position":2,"is_corresponding":false},{"id":1531571,"name":"Mario De Caroli","orcid":null,"position":3,"is_corresponding":false},{"id":1531572,"name":"Andrea Di Venanzio","orcid":null,"position":4,"is_corresponding":false},{"id":1531573,"name":"Giulia Maria Mariani","orcid":null,"position":5,"is_corresponding":false},{"id":1162603,"name":"Giacomo Baima","orcid":"0000-0002-9395-4967","position":6,"is_corresponding":false},{"id":1162602,"name":"Mario Aimetti","orcid":"0000-0003-0657-0787","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Outcomes of Active Periodontal Therapy in a Specialist University Setting Following\n                    <scp>EFP S3</scp>\n                    Treatment Guideline in Stage III–IV Periodontitis Patients","abstract":"<jats:title>ABSTRACT</jats:title>\n                  <jats:sec>\n                    <jats:title>Aim</jats:title>\n                    <jats:p>To describe the efficacy of steps I–II–III of periodontal therapy performed in a specialist university setting following EFP S3 treatment guideline and to assess factors associated with the achievement of endpoints of therapy (EoT).</jats:p>\n                  </jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods</jats:title>\n                    <jats:p>Records of 131 stage III–IV periodontitis patients were collected retrospectively. Residual pockets (probing pocket depth [PPD] 5 mm with bleeding on probing [BoP] or PPD ≥ 6 mm) after steps I–II (T1) received repeated subgingival instrumentation (RSI) or surgery and were re‐evaluated after 1 year (T2). EoT (no PPD ≥ 5 mm BoP+ and no PPD ≥ 6 mm) rate at T1 and T2 was computed, and predictors explored through multilevel analyses.</jats:p>\n                  </jats:sec>\n                  <jats:sec>\n                    <jats:title>Results</jats:title>\n                    <jats:p>At T1, EoT was 67.8%, with step III yielding an additional 90.0% of EoT in PPD = 5 mm BoP+ and 85.3% in PPD ≥ 6 mm. Factors negatively associated with EoT were: posterior teeth, furcation involvement (degree II–III), initial PPD, interproximal location and plaque. When considering only pockets ≥ 6 mm, factors were PPD at T1, type of intervention (resective surgery over RSI) and plaque at T2. Overall, 55.7% of patients reached EoT, 16.1% achieved ‘stable periodontitis’ (PPD ≤ 4 mm, no PPD = 4 mm BoP+, BoP &lt; 10%).</jats:p>\n                  </jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions</jats:title>\n                    <jats:p>Guideline‐based periodontal therapy achieved EoT targets in 93.3% of sites and 50% of patients with Stage III–IV periodontitis.</jats:p>\n                  </jats:sec>","is_dataset_classified":null,"base_score":1.0986122886681096,"endowment":1.0986122886681096,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"41554667","pmcid":null,"openalex_id":"https://openalex.org/W7124894013","authors":[],"funders":[],"total_grants":0,"fwci":16.5483,"citation_percentile":0.98200546,"influential_citations":0,"citation_trend":[{"year":2026,"count":2}],"oa_status":"closed","license":"http://doi.wiley.com/10.1002/tdm_license_1.1","oa_locations":[{"url":"https://onlinelibrary.wiley.com/doi/pdf/10.1111/jcpe.70087","host_type":"publisher"},{"url":"https://onlinelibrary.wiley.com/doi/full-xml/10.1111/jcpe.70087","host_type":"publisher"},{"url":"https://doi.org/10.1111/jcpe.70087","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/41554667","host_type":"repository"}],"fields_of_study":["Oral microbiology and periodontitis research","Dental Research and COVID-19","Dental Radiography and Imaging","Humans","Female","Treatment Outcome","Retrospective Studies","Middle Aged","Male","Periodontal Pocket","Practice Guidelines as Topic","Adult","Furcation Defects","Periodontal Index","Aged","Periodontitis","Chronic Periodontitis","Follow-Up Studies","Dental Plaque"],"mesh_terms":["Adult","Aged","Dental Plaque","Female","Follow-Up Studies","Humans","Male","Middle Aged","Periodontal Index","Periodontal Pocket","Periodontitis","Retrospective Studies","Treatment Outcome","Practice Guidelines as Topic","Furcation Defects","Chronic Periodontitis"],"keywords":["Guideline","Periodontitis","Stage (stratigraphy)","Periodontal disease","Gingival and periodontal pocket","Chronic periodontitis","Periodontal Diseases","Periodontal Surgery","Non‐surgical Therapy","Efp S3 Guideline","Therapy Endpoints"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-28T14:18:25.226818Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}