{"doi":"10.1111/jch.14934","title":"Association Between Blood Pressure Variation During Dialysis and Cardio‐Cerebrovascular Events","abstract":"<jats:title>ABSTRACT</jats:title><jats:p>In hemodialysis patients, blood pressure variability (BPV) is associated with cardiovascular events and all‐cause mortality. However, previous research has predominantly concentrated on the predialysis BPV. In contrast, intradialytic BPV, reflecting the cardiovascular regulatory function during the process of rapid clearance of volume overload, holds greater relevance to the prognosis of patients. In this study, a latent category trajectory model was used to identify the patterns of intradialytic BPV and analyze the association between intradialytic BPV and the cardio‐cerebrovascular events and other clinical outcomes. We found the variation of intradialytic systolic blood pressure (SBP) was associated with the risk of cardio‐cerebrovascular events in hemodialysis patients. Patients in “SBP Class 4” and “SBP Class 3” subgroups were associated with the occurrence of cardio‐cerebrovascular events and the number of cardio‐cerebrovascular event hospitalizations during the follow‐up period. This indicates that the variation pattern of intradialytic SBP results from the comprehensive action of various BP regulatory mechanisms in the body, which can reflect the level of cardiovascular regulatory function in hemodialysis patients and serve as a predictor of recent adverse cardio‐cerebrovascular events.</jats:p>","journal":"The Journal of Clinical Hypertension","year":2025,"id":611564,"datarank":0.16479184330021646,"base_score":1.0986122886681096,"endowment":1.0986122886681096,"self_citation_contribution":0.16479184330021646,"citation_network_contribution":0.0,"self_endowment_contribution":0.16479184330021646,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1574038,"name":"Rujia Ye","orcid":null,"position":1,"is_corresponding":false},{"id":1574039,"name":"Qiaorui Yang","orcid":null,"position":2,"is_corresponding":false},{"id":1574040,"name":"Mengfan Yang","orcid":null,"position":3,"is_corresponding":false},{"id":1574041,"name":"Riping Yin","orcid":null,"position":4,"is_corresponding":false},{"id":1574042,"name":"Dongxue Zhao","orcid":null,"position":5,"is_corresponding":false},{"id":481544,"name":"Junfen Fan","orcid":"0000-0003-1892-5768","position":6,"is_corresponding":false},{"id":1574043,"name":"Hongzhen Ma","orcid":null,"position":7,"is_corresponding":false},{"id":1122230,"name":"Yiwei Shen","orcid":"0000-0003-4594-5035","position":8,"is_corresponding":false},{"id":1335728,"name":"Hong Xia","orcid":null,"position":9,"is_corresponding":false},{"id":1574044,"name":"Wenze Jiang","orcid":null,"position":10,"is_corresponding":false},{"id":1574045,"name":"Keda Lu","orcid":null,"position":11,"is_corresponding":false},{"id":1574037,"name":"Zhenliang Fan","orcid":"0000-0002-3508-6954","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Association Between Blood Pressure Variation During Dialysis and Cardio‐Cerebrovascular Events","abstract":"<jats:title>ABSTRACT</jats:title><jats:p>In hemodialysis patients, blood pressure variability (BPV) is associated with cardiovascular events and all‐cause mortality. However, previous research has predominantly concentrated on the predialysis BPV. In contrast, intradialytic BPV, reflecting the cardiovascular regulatory function during the process of rapid clearance of volume overload, holds greater relevance to the prognosis of patients. In this study, a latent category trajectory model was used to identify the patterns of intradialytic BPV and analyze the association between intradialytic BPV and the cardio‐cerebrovascular events and other clinical outcomes. We found the variation of intradialytic systolic blood pressure (SBP) was associated with the risk of cardio‐cerebrovascular events in hemodialysis patients. Patients in “SBP Class 4” and “SBP Class 3” subgroups were associated with the occurrence of cardio‐cerebrovascular events and the number of cardio‐cerebrovascular event hospitalizations during the follow‐up period. This indicates that the variation pattern of intradialytic SBP results from the comprehensive action of various BP regulatory mechanisms in the body, which can reflect the level of cardiovascular regulatory function in hemodialysis patients and serve as a predictor of recent adverse cardio‐cerebrovascular events.</jats:p>","is_dataset_classified":null,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"39654485","pmcid":"PMC11774084","openalex_id":"https://openalex.org/W4405210053","authors":[],"funders":[{"funder_name":"National Natural Science Foundation of China","grant_id":"82104756","title":null},{"funder_name":"Science Foundation of Zhejiang province","grant_id":"LQ22H270002","title":null}],"total_grants":2,"fwci":0.297,"citation_percentile":0.65479367,"influential_citations":0,"citation_trend":[{"year":2026,"count":1}],"oa_status":"gold","license":"cc-by-nc","oa_locations":[{"url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jch.14934","host_type":"journal"},{"url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jch.14934","host_type":"publisher"},{"url":"https://onlinelibrary.wiley.com/doi/pdf/10.1111/jch.14934","host_type":"publisher"},{"url":"https://doi.org/10.1111/jch.14934","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/39654485","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11774084","host_type":"repository"},{"url":"https://doaj.org/article/4dd757c0153f473ba4132d7777d7cf69","host_type":"repository"},{"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11774084/pdf/JCH-27-e14934.pdf","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC11774084","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC11774084?pdf=render","host_type":"Europe_PMC"}],"fields_of_study":["Blood Pressure and Hypertension Studies","Cardiovascular Health and Disease Prevention","Heart Rate Variability and Autonomic Control","Humans","Renal Dialysis","Blood Pressure","Male","Female","Middle Aged","Aged","Cardiovascular Diseases","Cerebrovascular Disorders","Prognosis","Kidney Failure, Chronic","Risk Factors","Hypertension","Blood Pressure Determination"],"mesh_terms":["Aged","Blood Pressure","Blood Pressure Determination","Cardiovascular Diseases","Cerebrovascular Disorders","Female","Renal Dialysis","Hospitalization","Humans","Hypertension","Kidney Failure, Chronic","Male","Middle Aged","Prognosis","Risk Factors"],"keywords":["Medicine","Blood pressure","Hemodialysis","Cardiology","Internal medicine","Dialysis","Blood pressure variability","Cardio‐cerebrovascular Events","Latent Category Trajectory Model"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-01T20:40:50.850035Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}