{"doi":"10.1111/jch.12382","title":"Carotid to Femoral Pulse Wave Velocity Reflects the Extent of Coronary Artery Disease","abstract":"<jats:p>Arterial stiffness is a well<jats:bold>‐</jats:bold>established risk factor for cardiovascular disease and mortality. Carotid to femoral pulse wave velocity (cf<jats:styled-content style=\"fixed-case\">PWV</jats:styled-content>) as a measure of arterial stiffness was obtained in 155 (47 women; 67.2±9.1 years, range 44–87 years) patients with detected coronary artery disease (<jats:styled-content style=\"fixed-case\">CAD</jats:styled-content>) scheduled for coronary artery bypass surgery. The authors set out to analyze how cf<jats:styled-content style=\"fixed-case\">PWV</jats:styled-content> in <jats:styled-content style=\"fixed-case\">CAD</jats:styled-content> patients correlates with reference values for healthy, normotensive volunteers and whether cf<jats:styled-content style=\"fixed-case\">PWV</jats:styled-content> values reflect the extent of <jats:styled-content style=\"fixed-case\">CAD</jats:styled-content>. cfPWV was measured with an oscillometric device. Mean cf<jats:styled-content style=\"fixed-case\">PWV</jats:styled-content> value of <jats:styled-content style=\"fixed-case\">CAD</jats:styled-content> patients was 9.3±1.9 m/s vs 7.7±1.1 m/s in healthy volunteers (<jats:italic>P</jats:italic>&lt;.0001). In a multiple regression model, age (<jats:italic>P</jats:italic>&lt;.0001), sex (<jats:italic>P</jats:italic>=.006), systolic arterial pressure (<jats:italic>P</jats:italic>=.04), mean arterial pressure (<jats:italic>P</jats:italic>=.04), and severity of <jats:styled-content style=\"fixed-case\">CAD</jats:styled-content> (<jats:italic>P</jats:italic>&lt;.001) emerged as independent predictive markers for cf<jats:styled-content style=\"fixed-case\">PWV</jats:styled-content> in <jats:styled-content style=\"fixed-case\">CAD</jats:styled-content> patients. This study established reference values for cf<jats:styled-content style=\"fixed-case\">PWV</jats:styled-content> in <jats:styled-content style=\"fixed-case\">CAD</jats:styled-content> patients measured with an oscillometric device and confirmed the strong association between arterial stiffness and severity of CAD.</jats:p>","journal":"The Journal of Clinical Hypertension","year":2014,"id":606549,"datarank":0.515098080672772,"base_score":3.4339872044851463,"endowment":3.4339872044851463,"self_citation_contribution":0.515098080672772,"citation_network_contribution":0.0,"self_endowment_contribution":0.515098080672772,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":30,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1557171,"name":"Marcus Riemer","orcid":null,"position":1,"is_corresponding":false},{"id":1557172,"name":"Christian Erbs","orcid":null,"position":2,"is_corresponding":false},{"id":1557173,"name":"Alexander Plehn","orcid":null,"position":3,"is_corresponding":false},{"id":1557174,"name":"Alexander Navarrete Santos","orcid":null,"position":4,"is_corresponding":false},{"id":1557175,"name":"Andreas Wienke","orcid":null,"position":5,"is_corresponding":false},{"id":1557176,"name":"Rolf‐Edgar Silber","orcid":null,"position":6,"is_corresponding":false},{"id":264266,"name":"Andreas Simm","orcid":"0000-0002-5494-7000","position":7,"is_corresponding":false},{"id":1557170,"name":"Britt Hofmann","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Carotid to Femoral Pulse Wave Velocity Reflects the Extent of Coronary Artery Disease","abstract":"<jats:p>Arterial stiffness is a well<jats:bold>‐</jats:bold>established risk factor for cardiovascular disease and mortality. Carotid to femoral pulse wave velocity (cf<jats:styled-content style=\"fixed-case\">PWV</jats:styled-content>) as a measure of arterial stiffness was obtained in 155 (47 women; 67.2±9.1 years, range 44–87 years) patients with detected coronary artery disease (<jats:styled-content style=\"fixed-case\">CAD</jats:styled-content>) scheduled for coronary artery bypass surgery. The authors set out to analyze how cf<jats:styled-content style=\"fixed-case\">PWV</jats:styled-content> in <jats:styled-content style=\"fixed-case\">CAD</jats:styled-content> patients correlates with reference values for healthy, normotensive volunteers and whether cf<jats:styled-content style=\"fixed-case\">PWV</jats:styled-content> values reflect the extent of <jats:styled-content style=\"fixed-case\">CAD</jats:styled-content>. cfPWV was measured with an oscillometric device. Mean cf<jats:styled-content style=\"fixed-case\">PWV</jats:styled-content> value of <jats:styled-content style=\"fixed-case\">CAD</jats:styled-content> patients was 9.3±1.9 m/s vs 7.7±1.1 m/s in healthy volunteers (<jats:italic>P</jats:italic>&lt;.0001). In a multiple regression model, age (<jats:italic>P</jats:italic>&lt;.0001), sex (<jats:italic>P</jats:italic>=.006), systolic arterial pressure (<jats:italic>P</jats:italic>=.04), mean arterial pressure (<jats:italic>P</jats:italic>=.04), and severity of <jats:styled-content style=\"fixed-case\">CAD</jats:styled-content> (<jats:italic>P</jats:italic>&lt;.001) emerged as independent predictive markers for cf<jats:styled-content style=\"fixed-case\">PWV</jats:styled-content> in <jats:styled-content style=\"fixed-case\">CAD</jats:styled-content> patients. This study established reference values for cf<jats:styled-content style=\"fixed-case\">PWV</jats:styled-content> in <jats:styled-content style=\"fixed-case\">CAD</jats:styled-content> patients measured with an oscillometric device and confirmed the strong association between arterial stiffness and severity of CAD.</jats:p>","is_dataset_classified":null,"base_score":3.4339872044851463,"endowment":3.4339872044851463,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"25080855","pmcid":null,"openalex_id":"https://openalex.org/W2078297210","authors":[],"funders":[],"total_grants":0,"fwci":0.9371,"citation_percentile":0.77175474,"influential_citations":0,"citation_trend":[{"year":2014,"count":1},{"year":2016,"count":3},{"year":2017,"count":1},{"year":2018,"count":3},{"year":2019,"count":6},{"year":2020,"count":2},{"year":2021,"count":6},{"year":2022,"count":2},{"year":2023,"count":1},{"year":2024,"count":1},{"year":2025,"count":3},{"year":2026,"count":1}],"oa_status":"bronze","license":"http://onlinelibrary.wiley.com/termsAndConditions#vor","oa_locations":[{"url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jch.12382","host_type":"journal"},{"url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jch.12382","host_type":"publisher"},{"url":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fjch.12382","host_type":"publisher"},{"url":"https://onlinelibrary.wiley.com/doi/pdf/10.1111/jch.12382","host_type":"publisher"},{"url":"https://doi.org/10.1111/jch.12382","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/25080855","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8031522","host_type":"repository"}],"fields_of_study":["Cardiovascular Health and Disease Prevention","Blood Pressure and Hypertension Studies","Cardiovascular Function and Risk Factors","Adult","Aged","Aged, 80 and over","Blood Pressure","Carotid Arteries","Case-Control Studies","Coronary Artery Disease","Female","Femoral Artery","Humans","Male","Middle Aged","Oscillometry","Predictive Value of Tests","Pulse Wave Analysis","Reference Values","Regional Blood Flow","Regression Analysis","Risk Factors","Severity of Illness Index","Vascular Stiffness"],"mesh_terms":["Adult","Aged","Aged, 80 and over","Blood Pressure","Carotid Arteries","Coronary Artery Disease","Female","Femoral Artery","Humans","Male","Middle Aged","Oscillometry","Predictive Value of Tests","Reference Values","Regional Blood Flow","Regression Analysis","Risk Factors","Severity of Illness Index","Case-Control Studies","Vascular Stiffness","Pulse Wave Analysis"],"keywords":["Medicine","Pulse wave velocity","Cardiology","Arterial stiffness","Coronary artery disease","Internal medicine","Blood pressure","Pulse pressure","Femoral artery","Carotid arteries","CAD"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-30T04:45:14.214863Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}