{"doi":"10.1111/ijpo.12964","title":"Neighbourhood socio‐economic environment predicts adiposity and obesity risk in children under two","abstract":"<jats:title>Summary</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>Neighbourhood socio‐economic environment (SEE) is associated with obesity in older children and adults, but little is known about this relationship in younger children. Breastfeeding is an important preventative of adiposity in childhood, but its relationship with neighbourhood SEE is unknown.</jats:p></jats:sec><jats:sec><jats:title>Aims</jats:title><jats:p>We assessed differences in adiposity and obesity in children before age two by neighbourhood SEE, controlling for family socio‐demographics and breastfeeding duration.</jats:p></jats:sec><jats:sec><jats:title>Materials and Methods</jats:title><jats:p>Family socio‐demographics, child body mass index <jats:italic>z</jats:italic> scores (BMI<jats:italic>z</jats:italic>), and breastfeeding duration were collected at periodic study visits from participants in PREVAIL (<jats:italic>n</jats:italic> = 245), a birth cohort in Cincinnati, OH. Addresses were assigned a Deprivation Index score, a validated measure of SEE, and dichotomized into highest SEE (least deprived quartile of scores) and not highest SEE (remaining quartiles). Longitudinal and Poisson models assessed differences in BMI<jats:italic>z</jats:italic> by SEE over the second year of life and obesity risk at age two, respectively (highest SEE, <jats:italic>reference</jats:italic>), while attenuation of obesity risk by breastfeeding duration was tested in mediation models.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Residing outside of the highest SEE neighbourhoods was associated with an increased BMI<jats:italic>z</jats:italic> of 0.04 (95%CI 0.02, 0.06) per month of life and increased obesity risk at age two (aRR: 3.7, 95%CI 1.2, 16.2), controlling for family socio‐demographics. Breastfeeding duration attenuated &gt;9% of the obesity risk attributable to SEE (mediated RR: 3.4, 95%CI 1.1, 14.8).</jats:p></jats:sec><jats:sec><jats:title>Discussion</jats:title><jats:p>In the PREVAIL Cohort, residing outside of the highest SEE neighbourhoods predicted a significant increase in BMI<jats:italic>z</jats:italic> and obesity risk in children before age two, a relationship that was partially mediated by breastfeeding duration.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>Breastfeeding support may play an important role in reducing obesity rates in children in lower SEE neighbourhoods.</jats:p></jats:sec>","journal":"Pediatric Obesity","year":2022,"id":649833,"datarank":0.3596842909197557,"base_score":2.3978952727983707,"endowment":2.3978952727983707,"self_citation_contribution":0.3596842909197557,"citation_network_contribution":0.0,"self_endowment_contribution":0.3596842909197557,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":10,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1694185,"name":"Allison R. Burrell","orcid":null,"position":1,"is_corresponding":false},{"id":354124,"name":"Cole Brokamp","orcid":"0000-0002-0289-3151","position":2,"is_corresponding":false},{"id":310341,"name":"Rachel M. Burke","orcid":"0000-0002-5678-5826","position":3,"is_corresponding":false},{"id":367293,"name":"Sarah C. Couch","orcid":"0000-0003-1042-0490","position":4,"is_corresponding":false},{"id":611915,"name":"Liang Niu","orcid":"0009-0000-9048-5483","position":5,"is_corresponding":false},{"id":310342,"name":"Claire P. Mattison","orcid":"0000-0001-8558-8779","position":6,"is_corresponding":false},{"id":1694186,"name":"Alexandra Piasecki","orcid":null,"position":7,"is_corresponding":false},{"id":236977,"name":"Daniel C. Payne","orcid":"0000-0002-5871-911X","position":8,"is_corresponding":false},{"id":1694188,"name":"Mary A. Staat","orcid":null,"position":9,"is_corresponding":false},{"id":550150,"name":"Ardythe L. Morrow","orcid":"0000-0002-1126-4525","position":10,"is_corresponding":false},{"id":979155,"name":"Shannon C Conrey","orcid":"0000-0003-3715-5842","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Neighbourhood socio‐economic environment predicts adiposity and obesity risk in children under two","abstract":"<jats:title>Summary</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>Neighbourhood socio‐economic environment (SEE) is associated with obesity in older children and adults, but little is known about this relationship in younger children. Breastfeeding is an important preventative of adiposity in childhood, but its relationship with neighbourhood SEE is unknown.</jats:p></jats:sec><jats:sec><jats:title>Aims</jats:title><jats:p>We assessed differences in adiposity and obesity in children before age two by neighbourhood SEE, controlling for family socio‐demographics and breastfeeding duration.</jats:p></jats:sec><jats:sec><jats:title>Materials and Methods</jats:title><jats:p>Family socio‐demographics, child body mass index <jats:italic>z</jats:italic> scores (BMI<jats:italic>z</jats:italic>), and breastfeeding duration were collected at periodic study visits from participants in PREVAIL (<jats:italic>n</jats:italic> = 245), a birth cohort in Cincinnati, OH. Addresses were assigned a Deprivation Index score, a validated measure of SEE, and dichotomized into highest SEE (least deprived quartile of scores) and not highest SEE (remaining quartiles). Longitudinal and Poisson models assessed differences in BMI<jats:italic>z</jats:italic> by SEE over the second year of life and obesity risk at age two, respectively (highest SEE, <jats:italic>reference</jats:italic>), while attenuation of obesity risk by breastfeeding duration was tested in mediation models.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Residing outside of the highest SEE neighbourhoods was associated with an increased BMI<jats:italic>z</jats:italic> of 0.04 (95%CI 0.02, 0.06) per month of life and increased obesity risk at age two (aRR: 3.7, 95%CI 1.2, 16.2), controlling for family socio‐demographics. Breastfeeding duration attenuated &gt;9% of the obesity risk attributable to SEE (mediated RR: 3.4, 95%CI 1.1, 14.8).</jats:p></jats:sec><jats:sec><jats:title>Discussion</jats:title><jats:p>In the PREVAIL Cohort, residing outside of the highest SEE neighbourhoods predicted a significant increase in BMI<jats:italic>z</jats:italic> and obesity risk in children before age two, a relationship that was partially mediated by breastfeeding duration.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>Breastfeeding support may play an important role in reducing obesity rates in children in lower SEE neighbourhoods.</jats:p></jats:sec>","is_dataset_classified":null,"base_score":2.3978952727983707,"endowment":2.3978952727983707,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"36350200","pmcid":"PMC9788269","openalex_id":"https://openalex.org/W4292289378","authors":[],"funders":[{"funder_name":"National Center for Immunization and Respiratory Diseases","grant_id":"IP16‐004","title":null},{"funder_name":"National Institute of Environmental Health Sciences","grant_id":"5 T32 ES 10957‐18","title":null},{"funder_name":"NIEHS NIH HHS","grant_id":"T32 ES010957","title":null},{"funder_name":"NIDDK NIH HHS","grant_id":"P30 DK078392","title":null},{"funder_name":"National Institutes of Health","grant_id":"5T32ES010957-23","title":"Molecular Epidemiology in Children's Environmental Health Training Program (MECEH)"}],"total_grants":5,"fwci":1.7444,"citation_percentile":0.83755909,"influential_citations":0,"citation_trend":[{"year":2022,"count":1},{"year":2023,"count":1},{"year":2024,"count":3},{"year":2025,"count":4},{"year":2026,"count":1}],"oa_status":"hybrid","license":"cc-by","oa_locations":[{"url":"https://doi.org/10.1111/ijpo.12964","host_type":"journal"},{"url":"https://doi.org/10.1111/ijpo.12964","host_type":"publisher"},{"url":"https://onlinelibrary.wiley.com/doi/pdf/10.1111/ijpo.12964","host_type":"publisher"},{"url":"https://onlinelibrary.wiley.com/doi/full-xml/10.1111/ijpo.12964","host_type":"publisher"},{"url":"https://pubmed.ncbi.nlm.nih.gov/36350200","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9788269","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC9788269","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC9788269?pdf=render","host_type":"Europe_PMC"},{"url":"http://dx.doi.org/10.1111/ijpo.12964","host_type":""}],"fields_of_study":["Obesity, Physical Activity, Diet","Breastfeeding Practices and Influences","Health disparities and outcomes","03 medical and health sciences","0302 clinical medicine","0305 other medical science","Child","Adult","Female","Humans","Adiposity","Pediatric Obesity","Socioeconomic Factors","Residence Characteristics","Body Mass Index"],"mesh_terms":["Adult","Child","Female","Humans","Residence Characteristics","Socioeconomic Factors","Body Mass Index","Adiposity","Pediatric Obesity"],"keywords":["Medicine","Breastfeeding","Obesity","Demography","Body mass index","Quartile","Neighbourhood (mathematics)","Cohort","Childhood obesity","Relative risk","Poisson regression","Overweight","Gerontology","Pediatrics","Environmental health","Population","Confidence interval","Internal medicine","Health Disparities","Social Determinants Of Health","Child Obesity","Socio-economic Environment","Adult","Pediatric Obesity","Socioeconomic Factors","Residence Characteristics","Humans","Female","Child","Original Research","Adiposity"],"sdg_mappings":[{"sdg_number":2,"sdg_label":"2. 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