{"doi":"10.1111/hiv.13366","title":"Effect of <scp>HIV</scp> and antiretroviral therapy use on body weight changes in a cohort of U.S. veterans living with and without <scp>HIV</scp>","abstract":"OBJECTIVE: People living with HIV have high rates of obesity and obesity-related comorbidities. Our study sought to evaluate weight trajectory in a retrospective cohort of people living with HIV and matched HIV-negative veterans (controls) and to evaluate risk factors for weight gain. METHODS: This was a retrospective database analysis of data extracted from the VA Corporate Data Warehouse that included people living with HIV (n = 22 421) and age-matched HIV-negative controls (n = 63 072). The main outcomes were baseline body weight and weight change from baseline at 1, 2, and 5 years after diagnosis (baseline visit for controls). RESULTS: Body weight at baseline was lower in people living with HIV than in controls. People living with HIV on antiretroviral therapy (ART) gained more weight than did controls. In a sub-analysis of ART-exposed people living with HIV, age >50 years, African American race, body mass index (BMI) <25, CD4 ≤200, and HIV diagnosis year after 2000 were associated with more weight gain at year 1. Nucleoside reverse transcriptase inhibitors (NRTI) plus non-NRTIs (NNRTIs) were associated with less weight gain than NRTIs plus protease inhibitors, NRTIs plus integrase inhibitors, or NRTIs plus other agents at year 1. CONCLUSIONS: Among US veterans, those living with HIV had lower rates of obesity than age-matched HIV-negative controls; however, primarily in the first 2 years after starting ART, people living with HIV gained more weight than did controls.","journal":"HIV Medicine","year":2022,"id":283819,"datarank":0.48786241005702696,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"self_citation_contribution":0.29188652235829704,"citation_network_contribution":0.19597588769872992,"self_endowment_contribution":0.29188652235829704,"citer_contribution":0.19597588769872992,"corpus_percentile":60.78749903303164,"corpus_rank":5070,"citation_count":6,"citer_count":6,"citers_with_citation_signal":4,"citers_with_endowment":4,"datacite_reuse_total":0,"is_dataset":true,"is_dataset_confidence":0.6183,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":430084,"name":"Yongquan Dong","orcid":"0000-0001-7205-9931","position":1,"is_corresponding":false},{"id":75217,"name":"Peter Richardson","orcid":"0000-0002-3349-345X","position":2,"is_corresponding":false},{"id":430085,"name":"Jennifer R. Kramer","orcid":"0000-0003-2953-4949","position":3,"is_corresponding":false},{"id":793201,"name":"Christine Hartman","orcid":"0000-0002-8077-0026","position":4,"is_corresponding":false},{"id":793200,"name":"Kathryn E. Royse","orcid":"0000-0002-6828-1449","position":5,"is_corresponding":false},{"id":287876,"name":"Donna L. White","orcid":"0000-0003-0297-2949","position":6,"is_corresponding":false},{"id":292068,"name":"Elizabeth Y. Chiao","orcid":"0000-0001-5752-2916","position":7,"is_corresponding":false},{"id":363495,"name":"José M. Garcia","orcid":"0000-0002-4245-1753","position":0,"is_corresponding":true}],"reference_count":27,"raw_metadata":null,"created_at":"2026-07-19T00:29:28.452697Z","pmid":"35929183","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}