{"doi":"10.1111/evj.14300","title":"Follow‐up of the monitoring of equine rotavirus A infection in foals with diarrhoea in Argentina","abstract":"Study design: In vitro experiments.Methods: Three libraries were screened using a high-throughput in cellulo phenotypic-based protocol on their cytotoxicity and cytoprotective capabilities in EDc.Results: Out of more than 3000 molecules, 92 were identified as hit ones, and for 80 of them we confirmed their capability to decrease the EAV production in vitro.Most of the molecules already on market (with known mechanisms of action) seem to target ionic channel blockade and lipid metabolism modulation; both pathways are already known to impact viral replication of other Nidovirales virus such as SARS-CoV-2.Main limitation: Results need to be confirmed. Conclusion:These new molecules, showing antiviral capacities or expanding their antiviral spectrum, have been included in a translational global health research project to look for their antiviral capacity against other animal or human viruses (SARS-CoV-2, FCoV).Through the study of equine infectious disease, this project will increase the number of antiviral molecules that could be of use in future pandemics.","journal":"Equine Veterinary Journal","year":2024,"id":503778,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.6777,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[],"reference_count":0,"raw_metadata":null,"created_at":"2026-07-19T02:10:31.826282Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}