{"doi":"10.1111/evj.14219","title":"Sorbitol and lactose improve the biofilm production in genetically diverse strains of Argentinian <i>Streptococcus equi</i> subsp. <i>zooepidemicus</i>","abstract":"Results: Ten SMs demonstrating 100% growth inhibition were selected for further evaluation.The selected SMs demonstrated high growth inhibition against multidrug-resistant R. equi strains.The MIC and MBC of the SMs were found to be as low as 0.078 M and 0.156 M, respectively.Five out of 10 SMs demonstrated 100% inhibition of preformed biofilms at the concentration of 10 M.Similarly, all the selected SMs significantly inhibited ( p < 0.05) surviving R. equi inside the macrophage cells. Main limitations:The study only focuses on in vitro evaluation and lacks in vivo validation.The long-term stability and safety profiles of the identified SMs require further evaluation. Conclusion:Our study demonstrated that novel SMs can be used as alternatives to antibiotics for controlling R. equi infections.In the future, we will continue the evaluation of the SMs in vitro as well as test their efficacy on R. equi infected foals.","journal":"Equine Veterinary Journal","year":2024,"id":503780,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9573,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[],"reference_count":0,"raw_metadata":null,"created_at":"2026-07-19T02:10:31.826282Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}