{"doi":"10.1111/eip.70058","title":"Exploring Behavioural Patterns in Youth Predisposed to Bipolar Disorder and the Role of Interpersonal Trauma Using the Adolescent Brain Cognitive Development (<scp>ABCD</scp>) Dataset","abstract":"ABSTRACT Introduction Bipolar disorder (BD) is a severe, persistent disorder that causes functional impairment. Besides heritability, environmental factors, such as traumatic experience, impact the development of BD. Little is known about the early developmental signs of this disorder; therefore, this study aims to look at the impact of interpersonal trauma on the early developmental signs of BD. Specifically, differences in psychopathological behaviours were investigated between (1) at‐risk children and controls and (2) at‐risk children who experienced an interpersonal traumatic event and those who did not. Methods Using the Adolescent Brain Cognitive Development (ABCD) dataset, participants with a first‐degree relative with BD were identified ( N at‐risk = 625) and matched on sex and age to a control group ( N control = 625). The Kiddie Schedule for Affective Disorders and Schizophrenia (KSADS) was used to assess interpersonal trauma and psychopathological symptoms. The trauma ( N trauma = 198) and no‐trauma sub‐groups ( N no‐trauma = 428) were built from the at‐risk population. Group comparison was conducted on depressive, manic and anxiety symptoms. Results Compared to controls, at‐risk children exhibited a significantly greater number of manic symptoms at baseline and 2‐year follow‐up, and anxiety symptoms at follow‐up. No significant differences were found between the trauma and no‐trauma groups at either baseline or follow‐up. Discussion These results confirm the presence of early symptoms in at‐risk children, in line with the staging model of BD. Extended longitudinal research is needed to further investigate the potential specific role of trauma on its early behavioural patterns.","journal":"Early Intervention in Psychiatry","year":2025,"id":536220,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9291,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1337907,"name":"Danielle Penney","orcid":"0000-0002-5322-2294","position":1,"is_corresponding":false},{"id":1337908,"name":"Katie M. Lavigne","orcid":"0000-0002-3918-691X","position":2,"is_corresponding":false},{"id":1337909,"name":"Delphine Raucher‐Chéné","orcid":"0000-0002-5663-4454","position":3,"is_corresponding":false},{"id":1338377,"name":"Christina Ghaleb","orcid":null,"position":0,"is_corresponding":true}],"reference_count":45,"raw_metadata":null,"created_at":"2026-07-19T02:52:05.227140Z","pmid":"40444692","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}