{"doi":"10.1111/eip.13375","title":"Residential instability during adolescence predicts earlier age at onset of psychosis: The moderating role of extraversion","abstract":"INTRODUCTION: Residential instability (RI) during adolescence is associated with poor health outcomes. Also, extraversion has been shown to be a moderator of these associations. However, the associations between RI, extraversion, and age at onset of psychosis (AOP) remain unknown. METHODS: Data were collected from patients with first-episode psychosis (FEP). Linear regression models assessed the association between RI during adolescence and AOP. Extraversion was tested as a moderator using the interaction term RI-by-extraversion. RESULTS: Among 89 participants with FEP, both RI (adjusted β = -.278, p = .006) and the interaction term RI-by-extraversion (adjusted β = .290, p < .001) were associated with earlier AOP. Stratified analyses showed that RI was only significantly associated with earlier AOP among those with low extraversion (adjusted β = -.598, p < .001). CONCLUSIONS: RI predicted earlier AOP and this association was moderated by extraversion. These findings suggest that extraversion may buffer the negative relationship between RI and AOP. Future research should replicate these findings.","journal":"Early Intervention in Psychiatry","year":2023,"id":347332,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":11,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9185,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":411596,"name":"Elaine F. Walker","orcid":"0000-0002-9798-8101","position":1,"is_corresponding":false},{"id":1088823,"name":"Benjamin G. Druss","orcid":"0000-0003-0619-4873","position":2,"is_corresponding":false},{"id":1088824,"name":"Camille R. Murray","orcid":"0000-0002-2481-4485","position":3,"is_corresponding":false},{"id":760086,"name":"Michael T. Compton","orcid":"0000-0001-6835-2502","position":4,"is_corresponding":false},{"id":1078026,"name":"Benson S. Ku","orcid":"0000-0001-6994-8770","position":0,"is_corresponding":true}],"reference_count":17,"raw_metadata":null,"created_at":"2026-07-19T01:11:57.720122Z","pmid":"36650675","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}