{"doi":"10.1111/bjh.18899","title":"Enhanced <scp>IgG</scp> immune response to <scp>COVID</scp>‐19 vaccination in patients with sickle cell disease","abstract":"Patients with sickle cell disease (SCD) are considered to be immunocompromised, yet data on the antibody response to SARS-CoV-2 vaccination in SCD is limited. We investigated anti-SARS-CoV-2 IgG titres and overall neutralizing activity in 201 adults with SCD and demographically matched non-SCD controls. Unexpectedly, patients with SCD generate a more robust and durable COVID-19 vaccine IgG response compared to matched controls, though the neutralizing activity remained similar across both cohorts. These findings suggest that patients with SCD achieve a similar antibody response following COVID-19 vaccination compared to the general population, with implications for optimal vaccination strategies for patients with SCD.","journal":"British Journal of Haematology","year":2023,"id":362300,"datarank":0.32958368660043297,"base_score":2.1972245773362196,"endowment":2.1972245773362196,"self_citation_contribution":0.32958368660043297,"citation_network_contribution":0.0,"self_endowment_contribution":0.32958368660043297,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":8,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9541,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":558767,"name":"Narayanaiah Cheedarla","orcid":"0000-0001-6072-4383","position":1,"is_corresponding":false},{"id":226159,"name":"Hans Verkerke","orcid":"0000-0002-5152-0095","position":2,"is_corresponding":false},{"id":885666,"name":"Suneethamma Cheedarla","orcid":"0000-0003-1637-0500","position":3,"is_corresponding":false},{"id":693546,"name":"Shang‐Chuen Wu","orcid":"0000-0002-5284-5596","position":4,"is_corresponding":false},{"id":369614,"name":"Jeanne E. Hendrickson","orcid":"0000-0002-7928-3132","position":5,"is_corresponding":false},{"id":680214,"name":"Andrés Chang","orcid":"0000-0001-6679-9060","position":6,"is_corresponding":false},{"id":1115904,"name":"Morgan L. McLemore","orcid":null,"position":7,"is_corresponding":false},{"id":1115443,"name":"Fuad El Rassi","orcid":"0000-0002-8583-0526","position":8,"is_corresponding":false},{"id":226173,"name":"John D. Roback","orcid":"0000-0001-9952-2252","position":9,"is_corresponding":false},{"id":226168,"name":"Andrew S. Neish","orcid":"0000-0002-7090-0237","position":10,"is_corresponding":false},{"id":1115444,"name":"Ross M. Fasano","orcid":"0000-0002-8877-956X","position":11,"is_corresponding":false},{"id":226169,"name":"Sean R. Stowell","orcid":"0000-0002-1130-9551","position":12,"is_corresponding":false},{"id":700987,"name":"Hirotomo Nakahara","orcid":"0000-0001-7876-6557","position":0,"is_corresponding":true}],"reference_count":17,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-19T01:14:19.266946Z","pmid":"37287128","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}