{"doi":"10.1111/ajt.16079","title":"Clinical outcomes and serologic response in solid organ transplant recipients with COVID-19: A case series from the United States","abstract":"The coronavirus disease 2019 (COVID-19) pandemic caused by SARS coronavirus 2 (SARS-CoV-2) has caused significant morbidity and mortality for patients and stressed healthcare systems worldwide. The clinical features, disease course, and serologic response of COVID-19 among immunosuppressed patients such as solid organ transplant (SOT) recipients, who are at presumed risk for more severe disease, are not well characterized. We describe our institutional experience with COVID-19 among 10 SOT patients, including the clinical presentation, treatment modalities, and outcomes of 7 renal transplant recipients, 1 liver transplant recipient, 1 heart transplant recipient, and 1 lung transplant recipient. In addition, we report the serologic response in SOT recipients, documenting a positive IgG response in all 7 hospitalized patients. We also review the existing literature on COVID-19 in SOT recipients to consolidate the current knowledge on COVID-19 in the SOT population for the transplant community. The coronavirus disease 2019 (COVID-19) pandemic caused by SARS coronavirus 2 (SARS-CoV-2) has caused significant morbidity and mortality for patients and stressed healthcare systems worldwide. The clinical features, disease course, and serologic response of COVID-19 among immunosuppressed patients such as solid organ transplant (SOT) recipients, who are at presumed risk for more severe disease, are not well characterized. We describe our institutional experience with COVID-19 among 10 SOT patients, including the clinical presentation, treatment modalities, and outcomes of 7 renal transplant recipients, 1 liver transplant recipient, 1 heart transplant recipient, and 1 lung transplant recipient. In addition, we report the serologic response in SOT recipients, documenting a positive IgG response in all 7 hospitalized patients. We also review the existing literature on COVID-19 in SOT recipients to consolidate the current knowledge on COVID-19 in the SOT population for the transplant community.","journal":"American Journal of Transplantation","year":2020,"id":59397,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":67,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9619,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":92394,"name":"Charles Y. Chiu","orcid":"0000-0003-2915-2094","position":1,"is_corresponding":false},{"id":312335,"name":"Catherine DeVoe","orcid":"0000-0002-7861-274X","position":2,"is_corresponding":false},{"id":264777,"name":"Sarah B. Doernberg","orcid":"0000-0003-1727-6014","position":3,"is_corresponding":false},{"id":312336,"name":"Brian S. Schwartz","orcid":"0000-0003-2852-6808","position":4,"is_corresponding":false},{"id":107230,"name":"Charles Langelier","orcid":"0000-0002-6708-4646","position":5,"is_corresponding":false},{"id":239686,"name":"Timothy J. Henrich","orcid":"0000-0002-6684-0622","position":6,"is_corresponding":false},{"id":313254,"name":"Deborah S. Yokoe","orcid":null,"position":7,"is_corresponding":false},{"id":312337,"name":"John A. Davis","orcid":"0000-0002-0252-8402","position":8,"is_corresponding":false},{"id":311017,"name":"Steven R. Hays","orcid":"0000-0002-2887-8451","position":9,"is_corresponding":false},{"id":312338,"name":"Sindhu Chandran","orcid":"0000-0003-4547-3381","position":10,"is_corresponding":false},{"id":311018,"name":"Jasleen Kukreja","orcid":"0000-0003-2991-6680","position":11,"is_corresponding":false},{"id":92390,"name":"Dianna Ng","orcid":"0000-0001-5410-2326","position":12,"is_corresponding":false},{"id":252823,"name":"John C. Prostko","orcid":null,"position":13,"is_corresponding":false},{"id":313255,"name":"Russell Taylor","orcid":null,"position":14,"is_corresponding":false},{"id":92389,"name":"Kevin Reyes","orcid":"0000-0003-3708-444X","position":15,"is_corresponding":false},{"id":313256,"name":"Emma Bainbridge","orcid":null,"position":16,"is_corresponding":false},{"id":312339,"name":"Allison Bond","orcid":"0000-0002-6567-5557","position":17,"is_corresponding":false},{"id":312340,"name":"Peter Chin‐Hong","orcid":"0000-0001-9209-3395","position":18,"is_corresponding":false},{"id":312341,"name":"Jennifer M. Babik","orcid":"0000-0001-6914-4959","position":19,"is_corresponding":false},{"id":312334,"name":"Monica Fung","orcid":"0000-0002-1725-5259","position":0,"is_corresponding":true}],"reference_count":31,"raw_metadata":null,"created_at":"2026-07-18T21:07:59.189921Z","pmid":"32476258","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}