{"doi":"10.1111/add.15239","title":"All‐cause and cause‐specific mortality among people with regular or problematic cocaine use: a systematic review and meta‐analysis","abstract":"AIMS: To estimate pooled all-cause and cause-specific mortality risk for people with regular or problematic cocaine use. METHODS: Systematic review and meta-analysis of prospective or retrospective cohort studies or clinical trials (n ≥30) of people with regular or problematic cocaine use with data on all-cause or cause-specific mortality. Of 2808 papers, 28 were eligible and reported on 21 cohorts, with a total 170 019 individuals. Cohorts identified based on acute care for drug poisoning or other severe health presentation were excluded. Title/abstract screening was conducted by one reviewer; a second reviewer independently checked 10% of excluded studies. Two reviewers conducted full-text screening. Data were extracted by one reviewer and checked by a second. A customized review-specific study reporting quality/risk of bias tool was used. Data on crude mortality rates (CMR) and standardized mortality ratios were extracted for both all-cause and cause-specific mortality. Standardized mortality ratios were imputed where not provided by the author using extracted data and information from the Global Burden of Disease Study 2017. Data were pooled using a random-effects model. RESULTS: = 98.8%). The pooled all-cause standardized mortality ratio (SMR) was 6.13 (95% CI = 4.15, 9.05; n = 16 cohorts). Suicide (SMR = 6.26, 95% CI = 2.84, 13.80), accidental injury (SMR = 6.36, 95% CI = 4.18, 9.68), homicide (SMR = 9.38, 95% CI 3.45-25.48) and AIDS-related mortality (SMR = 23.12, 95% CI = 11.30, 47.31) were all elevated compared with age and sex peers in the general population. CONCLUSIONS: There are elevated rates of mortality among people with regular or problematic cocaine use for traumatic deaths and deaths attributable to infectious disease.","journal":"Addiction","year":2020,"id":66894,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":49,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.6969,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":301340,"name":"Lucy Thi Tran","orcid":"0000-0002-9711-1596","position":1,"is_corresponding":false},{"id":301343,"name":"Sarah Larney","orcid":"0000-0002-5602-4963","position":2,"is_corresponding":false},{"id":354207,"name":"Emily Stockings","orcid":"0000-0001-5349-951X","position":3,"is_corresponding":false},{"id":301342,"name":"Thomas Santo","orcid":"0000-0002-1218-3946","position":4,"is_corresponding":false},{"id":3376,"name":"Hayley E. Jones","orcid":"0000-0002-4265-2854","position":5,"is_corresponding":false},{"id":48878,"name":"Damian Santomauro","orcid":"0000-0002-6630-5435","position":6,"is_corresponding":false},{"id":22455,"name":"Louisa Degenhardt","orcid":"0000-0002-8513-2218","position":7,"is_corresponding":false},{"id":340312,"name":"Amy Peacock","orcid":"0000-0002-5705-2026","position":0,"is_corresponding":true}],"reference_count":63,"raw_metadata":null,"created_at":"2026-07-18T21:14:50.590588Z","pmid":"32857457","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}