{"doi":"10.1111/acer.15521","title":"A randomized controlled trial of Native <scp>CHOICES</scp>: Impact on alcohol‐exposed pregnancy risk reduction among American Indian and Alaska Native women","abstract":"BACKGROUND: Prevention of alcohol-exposed pregnancy (AEP) involves reducing risky alcohol consumption among women at-risk for pregnancy, using effective contraception among women drinking at risky levels to prevent pregnancy, or both. This study presents the outcomes of a randomized controlled trial assessing the efficacy of Native CHOICES, a culturally tailored adaptation of the CHOICES intervention, among American Indian/Alaska Native (AI/AN) women. METHODS: AI/AN women aged 18-44 who were at-risk for an AEP were randomly assigned in a 1:1 ratio to either the Native CHOICES intervention or a waitlist control group. Native CHOICES comprised two sessions of motivational interviewing and an elective contraception counseling session. Data were collected at baseline, and 6 weeks, 3 months, and 6 months postbaseline. Due to the pandemic, the intervention was at times delivered remotely. RESULTS: A total of 404 women participated: 199 in the control group and 205 in the intervention group. Sixty-seven percent of the intervention group received the intervention in-person, and 33% participated by telephone or video call. Sixty-four percent of women completed all follow-up visits. At the six-month follow-up, the intervention did not demonstrate a significant impact on AEP risk compared with the control arm when analyzing all the data (RR = 0.94; 95% confidence interval [CI]: 0.83-1.07). However, an exploratory subgroup analysis showed evidence of a reduction in AEP risk among participants who completed the study in-person before the COVID-19 pandemic (RR = 0.79; 95% CI: 0.63-0.98), which was not observed during or after the pandemic (RR = 1.06; 95% CI: 0.91-1.24). CONCLUSIONS: The Native CHOICES intervention did not show evidence of effectiveness overall. However, exploratory analyses offer some evidence that the intervention was effective prior to the pandemic.","journal":"Alcohol Clinical and Experimental Research","year":2024,"id":470234,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":3,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9565,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":412588,"name":"Carolyn Noonan","orcid":null,"position":1,"is_corresponding":false},{"id":722180,"name":"Kyra Oziel","orcid":"0000-0003-4802-2682","position":2,"is_corresponding":false},{"id":1304710,"name":"Karen Little Wounded","orcid":null,"position":3,"is_corresponding":false},{"id":1304711,"name":"S Darnell","orcid":null,"position":4,"is_corresponding":false},{"id":771829,"name":"Robert Rosenman","orcid":"0000-0002-3812-5824","position":5,"is_corresponding":false},{"id":341420,"name":"Marcia O’Leary","orcid":"0000-0001-8584-5659","position":6,"is_corresponding":false},{"id":412165,"name":"Richard F. MacLehose","orcid":"0000-0003-2041-3710","position":7,"is_corresponding":false},{"id":722181,"name":"Michelle Sarche","orcid":"0000-0001-9044-928X","position":8,"is_corresponding":false},{"id":264614,"name":"Dedra Buchwald","orcid":"0000-0002-9005-0110","position":9,"is_corresponding":false},{"id":722179,"name":"Jessica D. Hanson","orcid":"0000-0001-8867-2300","position":0,"is_corresponding":true}],"reference_count":45,"raw_metadata":null,"created_at":"2026-07-19T02:05:36.656771Z","pmid":"39710495","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}