{"doi":"10.1109/trpms.2024.3497774","title":"A Time-Walk and Timing-Shift Correction Method for Dual-Ended Readout TOF-DOI PET Detectors","abstract":"Positron emission tomography (PET) detectors suffer from time-walk when the leading edge discriminator is employed for timing pick-off as well as a timing-shift when thick crystals are utilized due to the depth-of-interaction (DOI) effect. In this study, a combined time-walk and timing-shift correction method was proposed for dual-ended readout PET detectors. To evaluate the proposed method, a pair of dual-ended readout PET detectors was constructed. Each detector was based on two Hamamatsu S14161-3050-08 silicon photomultiplier (SiPM) arrays coupled to both ends of an <inline-formula xmlns:mml=\"http://www.w3.org/1998/Math/MathML\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"> <tex-math notation=\"LaTeX\">$8\\times 8$ </tex-math></inline-formula> arrays of <inline-formula xmlns:mml=\"http://www.w3.org/1998/Math/MathML\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"> <tex-math notation=\"LaTeX\">$3.1\\times 3.1\\times 20~{\\mathrm { mm}}^{3}$ </tex-math></inline-formula> lutetium-yttrium oxyorthosilicate crystals with a 3.2-mm pitch. By employing the relationship between the energies and detected time differences of events, the time-walk and timing-shift were effectively corrected. The coincidence time resolution of the two detectors improved from <inline-formula xmlns:mml=\"http://www.w3.org/1998/Math/MathML\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"> <tex-math notation=\"LaTeX\">$260.7~\\pm ~1.0$ </tex-math></inline-formula> ps to <inline-formula xmlns:mml=\"http://www.w3.org/1998/Math/MathML\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"> <tex-math notation=\"LaTeX\">$229.4~\\pm ~1.0$ </tex-math></inline-formula> ps when a 400–650 keV energy window was used to select events. These results demonstrate the effectiveness of the proposed time-walk and timing-shift correction method.","journal":"IEEE Transactions on Radiation and Plasma Medical Sciences","year":2024,"id":458772,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":5,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9578,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1279695,"name":"Jiahao Xie","orcid":"0009-0005-2575-2027","position":1,"is_corresponding":false},{"id":256279,"name":"Jinyi Qi","orcid":"0000-0002-5428-0322","position":2,"is_corresponding":false},{"id":256275,"name":"Simon R. Cherry","orcid":"0000-0002-0155-5644","position":3,"is_corresponding":false},{"id":426566,"name":"Junwei Du","orcid":"0000-0002-1719-8266","position":4,"is_corresponding":false},{"id":1196826,"name":"H.B. Wang","orcid":"0009-0006-9182-9237","position":0,"is_corresponding":true}],"reference_count":37,"raw_metadata":null,"created_at":"2026-07-19T02:03:50.608887Z","pmid":"41050626","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}