{"doi":"10.1109/trpms.2023.3309771","title":"Design and Characterization of the Detector Readout Electronics Used in PETcoil: an RF-Penetrable TOF-PET Insert for PET/MRI","abstract":"This article presents a comprehensive description of the front-end detector readout electronics designed for positron emission tomography (PET) coil, an RF-penetrable TOF-PET insert for PET/MRI. The highly integrated front-end design is based on a mixed ASIC + FPGA approach and incorporates carefully designed power, thermal, and MR compatibility solutions. Experimental results show that the front-end design achieves excellent coincidence time resolution of <inline-formula xmlns:mml=\"http://www.w3.org/1998/Math/MathML\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"> <tex-math notation=\"LaTeX\">$\\mathrm {238.9 \\pm 0.3 ps }$ </tex-math></inline-formula> with real-time TDC bin width calibration and energy resolution of 10.9% ± 1.1%. The results also indicate good TOF position linearity and clear energy photopeaks. Additionally, the front-end design demonstrates the capability to handle high-count rate applications, with less than <inline-formula xmlns:mml=\"http://www.w3.org/1998/Math/MathML\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"> <tex-math notation=\"LaTeX\">$\\mathrm {0.005 \\! \\%}$ </tex-math></inline-formula> data loss or corruption observed when the count rate per SiPM channel increased from 3 to 20 kcps. The detector module temperature remained stable at <inline-formula xmlns:mml=\"http://www.w3.org/1998/Math/MathML\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"> <tex-math notation=\"LaTeX\">$23.9{^{\\circ} }\\text{C} \\pm $ </tex-math></inline-formula> 1.3°C throughout the entire 1-h experiment. These results indicate that this front-end design is feasible for high-sensitivity TOF PET applications.","journal":"IEEE Transactions on Radiation and Plasma Medical Sciences","year":2023,"id":361131,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":9,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9614,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":558362,"name":"Ilaria Sacco","orcid":null,"position":1,"is_corresponding":false},{"id":557676,"name":"Chen‐Ming Chang","orcid":"0000-0002-3509-1382","position":2,"is_corresponding":false},{"id":490894,"name":"Craig S. Levin","orcid":"0000-0002-4575-5074","position":3,"is_corresponding":false},{"id":557675,"name":"Qian Dong","orcid":"0000-0002-4250-7788","position":0,"is_corresponding":true}],"reference_count":35,"raw_metadata":null,"created_at":"2026-07-19T01:14:10.680991Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}