{"doi":"10.1109/iembs.2006.260311","title":"Microfabrication procedure of PDMS microbeam array using photolithography for laminin printing and piconewton force transduction on axons","abstract":null,"journal":"2006 International Conference of the IEEE Engineering in Medicine and Biology Society","year":2006,"id":687044,"datarank":0.10397207708399181,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"self_citation_contribution":0.10397207708399181,"citation_network_contribution":0.0,"self_endowment_contribution":0.10397207708399181,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1794877,"name":"Andrew J. Bohl","orcid":null,"position":1,"is_corresponding":false},{"id":1794880,"name":"Bradley E. Layton","orcid":null,"position":2,"is_corresponding":false},{"id":1794874,"name":"F. Mert Sasoglu","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Microfabrication procedure of PDMS microbeam array using photolithography for laminin printing and piconewton force transduction on axons","abstract":"The purpose of this paper is to introduce our design for transducing forces on the order of tens of piconewtons by optically measuring deflection of a microfabricated beam tip as it pulls on an array of flexible structures such as axons in an array of laminin-printed neurons. To achieve this we have designed polymeric beams with spring constants on the order of 10 pN/microm. We have fabricated circular microbeams with Sylgard polydimethylsiloxane (PDMS). The elastic modulus of PDMS was determined experimentally using a microscale and a micrometer at different concentrations of curing agent and base agent and found to be on the order of 100 kPa. The designed geometry is a 100x100 tapered microcone array with each beam having a length of 100 microm, and a base diameter of 10 microm. A SU-8 negative photoresist is etched using photolithography and used as a mold for PDMS soft lithography. PDMS was injected into the mold and the array peeled from the mold.","is_dataset_classified":null,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"17946983","pmcid":null,"openalex_id":"https://openalex.org/W2144386557","authors":[],"funders":[],"total_grants":0,"fwci":0.0,"citation_percentile":0.26717058,"influential_citations":0,"citation_trend":[{"year":2013,"count":1}],"oa_status":"closed","license":null,"oa_locations":[{"url":"http://xplorestaging.ieee.org/ielx5/4028925/4461641/04462388.pdf?arnumber=4462388","host_type":"publisher"},{"url":"https://doi.org/10.1109/iembs.2006.260311","host_type":""},{"url":"https://pubmed.ncbi.nlm.nih.gov/17946983","host_type":"repository"}],"fields_of_study":["Nanofabrication and Lithography Techniques","Force Microscopy Techniques and Applications","Cellular Mechanics and Interactions"],"mesh_terms":["Axons","Biocompatible Materials","Dimethylpolysiloxanes","Equipment Design","Laminin","Manometry","Miniaturization","Nylons","Photography","Stress, Mechanical","Transducers","Biosensing Techniques","Equipment Failure Analysis","Mechanotransduction, Cellular","Microarray Analysis"],"keywords":["Polydimethylsiloxane","Photolithography","Photoresist","Microfabrication","Materials science","Soft lithography","PDMS stamp","Microbeam","Microscale chemistry","Mold","Microfluidics","Lithography","Nanotechnology","Composite material","Optoelectronics","Optics","Fabrication"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-18T21:10:25.538195Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}