{"doi":"10.1109/iembs.2002.1053235","title":"cDNA microarray analysis of Dictyostelium development","abstract":null,"journal":"Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society] [Engineering in Medicine and Biology","year":2002,"id":597662,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1531181,"name":"N. Van Driessche","orcid":null,"position":1,"is_corresponding":false},{"id":145605,"name":"M. Katoh","orcid":null,"position":2,"is_corresponding":false},{"id":901144,"name":"M. Ibarra","orcid":null,"position":3,"is_corresponding":false},{"id":1531182,"name":"J. Halter","orcid":null,"position":4,"is_corresponding":false},{"id":1531183,"name":"G. Shaulsky","orcid":null,"position":5,"is_corresponding":false},{"id":590882,"name":"C.A. Shaw","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"cDNA microarray analysis of Dictyostelium development","abstract":"Dictyostelium discoideum are simple eukaryotes which are extensively studied in mathematical biology and molecular genetics. When starved, Dictyostelium cells aggregate and undergo a dramatic change from a solitary lifestyle to a multicellular structure containing spore and stalk cells. In genetically normal cells the process of Dictyostelium development requires approximately 24 hours. To monitor gene expression changes during the process of development, we have constructed a custom array representing approximately 7k distinct Dictyostelium genes representing approximately 2/3 of the genes in the genome. We have conducted a large number of 24 hour, 13 time point Dictyostelium microarray experiments. We find large patterns of change in gene expression across the developmental time course. We also find that the major patterns of gene expression are repeatable across separate laboratory preparations.","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"23304386","pmcid":null,"openalex_id":"https://openalex.org/W2099914126","authors":[],"funders":[],"total_grants":0,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[],"oa_status":"closed","license":"https://doi.org/10.15223/policy-029","oa_locations":[{"url":"http://xplorestaging.ieee.org/ielx5/8123/22474/01053235.pdf?arnumber=1053235","host_type":"publisher"},{"url":"https://doi.org/10.1109/iembs.2002.1053235","host_type":""}],"fields_of_study":["Cell Image Analysis Techniques","Gene expression and cancer classification","Advanced Biosensing Techniques and Applications"],"mesh_terms":[],"keywords":["Dictyostelium","Multicellular organism","Dictyostelium discoideum","Biology","Gene","DNA microarray","Gene expression","Slime mold","Microarray","Microarray analysis techniques","Genetics","Computational biology","Genome","Complementary DNA","Cell biology"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Life in Land"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-28T13:52:21.701682Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}