{"doi":"10.1109/embc48229.2022.9871608","title":"Analysis of the intended and actual orientations of directional deep brain stimulation leads across deep brain stimulation systems","abstract":"Deep brain stimulation (DBS) offers therapeutic benefits to patients suffering from a variety of treatment-resistant neurological and psychiatric disorders. The newest generation of DBS devices now offer directional leads, which utilize segmented electrodes to direct current asymmetrically to the neuronal tissue. Since segmented electrodes offer a larger degree of freedom for contact positioning, it is critical to assess how well the surgically intended and the actual orientation of the lead match to facilitate programming and allow appropriate interpretation of the therapeutic outcome. Postoperative image analysis algorithms, such as DiODe, are commonly used to determine DBS leads' actual orientation. In this work, we used DiODe to compare the deviation between intended and actual orientations of DBS leads across two most commonly implanted directional DBS systems, namely, Boston Scientific Cartesia™ and St. Jude Medical Infinity. This study is the first to investigate the rotation of leads from both DBS systems in a large group of 86 patients. Clinical Relevance- Our results quantify the variability between the surgically intended and actual orientations of Boston Scientific Vercise and St. Jude Medical Infinity DBS systems thus highlighting the need to develop more precise implantation procedures.","journal":"2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","year":2022,"id":299473,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":4,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9518,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":989301,"name":"Milina Michelle Miulli","orcid":"0000-0002-0207-2935","position":1,"is_corresponding":false},{"id":351146,"name":"Behzad Elahi","orcid":"0000-0002-4397-4935","position":2,"is_corresponding":false},{"id":281703,"name":"Joshua M. Rosenow","orcid":"0000-0001-7726-2496","position":3,"is_corresponding":false},{"id":352299,"name":"Mark J. Nolt","orcid":null,"position":4,"is_corresponding":false},{"id":351150,"name":"Laleh Golestanirad","orcid":"0000-0003-3869-6114","position":5,"is_corresponding":false},{"id":784017,"name":"Kaylee Henry","orcid":"0000-0002-3003-9681","position":0,"is_corresponding":true}],"reference_count":16,"raw_metadata":null,"created_at":"2026-07-19T00:31:44.904250Z","pmid":"36086443","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}