{"doi":"10.1109/access.2022.3154824","title":"Characterization of a Low-Profile, Flexible, and Acoustically Transparent Receive-Only MRI Coil Array for High Sensitivity MR-Guided Focused Ultrasound","abstract":"Magnetic resonance guided focused ultrasound (MRgFUS) is a non-invasive therapeutic modality for neurodegenerative diseases that employs real-time imaging and thermometry monitoring of targeted regions. MRI is used in guidance of ultrasound treatment; however, the MR image quality in current clinical applications is poor when using the vendor built-in body coil. We present an 8-channel, ultra-thin, flexible, and acoustically transparent receive-only head coil design (FUS-Flex) to improve the signal-to-noise ratio (SNR) and thus the quality of MR images during MRgFUS procedures. Acoustic simulations/experiments exhibit transparency of the FUS-Flex coil as high as 97% at 650 kHz. Electromagnetic simulations show a SNR increase of 13× over the body coil. In vivo results show an increase of the SNR over the body coil by a factor of 7.3 with 2× acceleration (equivalent to 11× without acceleration) in the brain of a healthy volunteer, which agrees well with simulation. These preliminary results show that the use of a FUS-Flex coil in MRgFUS surgery can increase MR image quality, which could yield improved focal precision, real-time intraprocedural anatomical imaging, and real-time 3D thermometry mapping.","journal":"IEEE Access","year":2022,"id":289172,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":5,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9635,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":638722,"name":"Fraser Robb","orcid":"0000-0002-1625-9709","position":1,"is_corresponding":false},{"id":802432,"name":"Victor Taracila","orcid":null,"position":2,"is_corresponding":false},{"id":970360,"name":"Vishwas Mishra","orcid":"0000-0001-8436-3041","position":3,"is_corresponding":false},{"id":802024,"name":"Jana Vincent","orcid":"0000-0002-2707-6000","position":4,"is_corresponding":false},{"id":465131,"name":"Henning U. Voss","orcid":"0000-0003-2811-2074","position":5,"is_corresponding":false},{"id":226556,"name":"Michael G. Kaplitt","orcid":"0000-0002-8979-2459","position":6,"is_corresponding":false},{"id":970361,"name":"J. Levi Chazen","orcid":"0000-0002-6146-2191","position":7,"is_corresponding":false},{"id":705027,"name":"Simone Winkler","orcid":"0000-0002-8080-9488","position":8,"is_corresponding":false},{"id":970359,"name":"Isabelle Saniour","orcid":"0000-0002-0349-0311","position":0,"is_corresponding":true}],"reference_count":41,"raw_metadata":null,"created_at":"2026-07-19T00:30:18.766838Z","pmid":"35600672","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}