{"doi":"10.1107/s2052252525007432","title":"<i>Magellon</i> – an extensible platform for cryo-EM data visualization, management and processing","abstract":"Single-particle cryo-electron microscopy (cryo-EM) has revolutionized structural biology by enabling high-resolution determination of macromolecular structures. However, the field faces challenges in data management, processing workflow integration and software extensibility. We present Magellon, an innovative cryo-EM software platform that addresses these challenges through a modern microservices architecture. Magellon consists of an extensible backend with a web based frontend that we call Magellon Viewer. Together, these combine high-performance computing capabilities with an intuitive user interface, enabling researchers to efficiently process and analyze cryo-EM data. The platform's distinguishing features include a plugin based architecture, distributed processing capabilities, comprehensive monitoring systems, and a novel approach to data organization and visualization. A key philosophy of the approach is that the Magellon backend provides a platform that uses robust industry-standard libraries to orchestrate computational tasks while offering users and developers flexibility in selecting the computational resources for performing calculations. Magellon represents a significant advancement in cryo-EM software infrastructure, offering flexibility, scalability and extensibility while maintaining ease of use.","journal":"IUCrJ","year":2025,"id":550924,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9525,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1446444,"name":"Puneeth Damodar","orcid":"0009-0000-3250-2337","position":1,"is_corresponding":false},{"id":1446802,"name":"Rupali R. Garje","orcid":null,"position":2,"is_corresponding":false},{"id":1446445,"name":"Frank H. Schotanus","orcid":"0009-0002-0318-8419","position":3,"is_corresponding":false},{"id":1446803,"name":"N. Sreekumaran Nair","orcid":null,"position":4,"is_corresponding":false},{"id":1446446,"name":"Lai Wei","orcid":"0000-0001-9632-2167","position":5,"is_corresponding":false},{"id":1446447,"name":"Jan-Hannes Schäfer","orcid":"0000-0001-8163-1629","position":6,"is_corresponding":false},{"id":287919,"name":"Gabriel C. Lander","orcid":"0000-0003-4921-1135","position":7,"is_corresponding":false},{"id":297932,"name":"Michael A. Cianfrocco","orcid":"0000-0002-2067-4999","position":8,"is_corresponding":false},{"id":308881,"name":"Scott M. Stagg","orcid":"0000-0001-8855-4152","position":9,"is_corresponding":false},{"id":1446801,"name":"Behdad Khoshbin","orcid":null,"position":0,"is_corresponding":true}],"reference_count":0,"raw_metadata":null,"created_at":"2026-07-19T02:54:20.915388Z","pmid":"40910510","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}