{"doi":"10.1104/pp.103.036897","title":"Brassinosteroids Interact with Auxin to Promote Lateral Root Development in Arabidopsis","abstract":"<jats:title>Abstract</jats:title>\n               <jats:p>Plant hormone brassinosteroids (BRs) and auxin exert some similar physiological effects likely through their functional interaction, but the mechanism for this interaction is unknown. In this study, we show that BRs are required for lateral root development in Arabidopsis and that BRs act synergistically with auxin to promte lateral root formation. BR perception is required for the transgenic expression of the β-glucuronidase gene fused to a synthetic auxin-inducible promoter (DR5::GUS) in root tips, while exogenous BR promotes DR5::GUS expression in the root tips and the stele region proximal to the root tip. BR induction of both lateral root formation and DR5::GUS expression is suppressed by the auxin transport inhibitor N-(1-naphthyl) phthalamic acid. Importantly, BRs promote acropetal auxin transport (from the base to the tip) in the root. Our observations indicate that BRs regulate auxin transport, providing a novel mechanism for hormonal interactions in plants and supporting the hypothesis that BRs promote lateral root development by increasing acropetal auxin transport.</jats:p>","journal":"Plant Physiology","year":2004,"id":24483,"datarank":11.364020636615676,"base_score":5.966146739123692,"endowment":5.966146739123692,"self_citation_contribution":0.8949220108685539,"citation_network_contribution":10.469098625747122,"self_endowment_contribution":0.8949220108685539,"citer_contribution":10.469098625747122,"corpus_percentile":null,"corpus_rank":null,"citation_count":389,"citer_count":200,"citers_with_citation_signal":200,"citers_with_endowment":200,"datacite_reuse_total":25,"is_dataset":false,"is_dataset_confidence":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":146766,"name":"Junjiang Shen","orcid":null,"position":1,"is_corresponding":false},{"id":146767,"name":"Shari R. Brady","orcid":null,"position":2,"is_corresponding":false},{"id":146713,"name":"Gloria K. Muday","orcid":null,"position":3,"is_corresponding":false},{"id":146768,"name":"Tadao Asami","orcid":null,"position":4,"is_corresponding":false},{"id":146769,"name":"Zhenbiao Yang","orcid":null,"position":5,"is_corresponding":false},{"id":146765,"name":"Fang Bao","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":5.966146739123692,"endowment":5.966146739123692,"datacite_reuse_total":25,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"15047895","pmcid":null,"openalex_id":"https://openalex.org/W2051111481","authors":[],"funders":[],"total_grants":0,"fwci":13.2271,"citation_percentile":0.98691565,"influential_citations":18,"citation_trend":[{"year":2012,"count":17},{"year":2013,"count":26},{"year":2014,"count":18},{"year":2015,"count":18},{"year":2016,"count":6},{"year":2017,"count":11},{"year":2018,"count":17},{"year":2019,"count":19},{"year":2020,"count":25},{"year":2021,"count":38},{"year":2022,"count":40},{"year":2023,"count":12},{"year":2024,"count":19},{"year":2025,"count":19},{"year":2026,"count":9}],"oa_status":"bronze","license":"https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model","oa_locations":[{"url":"https://academic.oup.com/plphys/article-pdf/134/4/1624/38701791/plphys_v134_4_1624.pdf","host_type":"journal"},{"url":"https://academic.oup.com/plphys/article-pdf/134/4/1624/38701791/plphys_v134_4_1624.pdf","host_type":"BRONZE"},{"url":"https://academic.oup.com/plphys/article-pdf/134/4/1624/38701791/plphys_v134_4_1624.pdf","host_type":"publisher"},{"url":"http://academic.oup.com/plphys/article-pdf/134/4/1624/38701791/plphys_v134_4_1624.pdf","host_type":"publisher"},{"url":"https://doi.org/10.1104/pp.103.036897","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/15047895","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/419836","host_type":"repository"}],"fields_of_study":["Plant Molecular Biology Research","Plant nutrient uptake and metabolism","Plant Reproductive Biology","Medicine","Biology","Environmental Science","Arabidopsis","Biological Transport","Brassinosteroids","Cholestanols","Drug Synergism","Gene Expression Regulation, Developmental","Gene Expression Regulation, Plant","Indoleacetic Acids","Phthalimides","Plant Growth Regulators","Plant Roots","Steroids, Heterocyclic"],"mesh_terms":["Biological Transport","Cholestanols","Drug Synergism","Indoleacetic Acids","Phthalimides","Plant Growth Regulators","Steroids, Heterocyclic","Arabidopsis","Gene Expression Regulation, Plant","Gene Expression Regulation, Developmental","Plant Roots","Brassinosteroids"],"keywords":["Auxin","Arabidopsis","Lateral root","Root (linguistics)","Plant development","Biology","Botany","Cell biology","Chemistry","Gene","Biochemistry","Non-nasa Center","Nasa Program Fundamental Space Biology","Nasa Discipline Plant Biology"],"sdg_mappings":[],"linked_datasets":[{"doi":"10.6084/m9.figshare.16599528.v1","title":"Additional file 1 of De novo transcriptome analysis provides insights into formation of in vitro adventitious root from leaf explants of Arnebia euchroma","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.16599528","title":"Additional file 1 of De novo transcriptome analysis provides insights into formation of in vitro adventitious root from leaf explants of Arnebia euchroma","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.16599531.v1","title":"Additional file 2 of De novo transcriptome analysis provides insights into formation of in vitro adventitious root from leaf explants of Arnebia euchroma","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.16599531","title":"Additional file 2 of De novo transcriptome analysis provides insights into formation of in vitro adventitious root from leaf explants of Arnebia euchroma","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.16599534.v1","title":"Additional file 3 of De novo transcriptome analysis provides insights into formation of in vitro adventitious root from leaf explants of Arnebia euchroma","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.16599534","title":"Additional file 3 of De novo transcriptome analysis provides insights into formation of in vitro adventitious root from leaf explants of Arnebia euchroma","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.20227024.v1","title":"Additional file 9 of Integrated transcriptome and hormonal analysis of naphthalene acetic acid-induced adventitious root formation of tea cuttings (Camellia sinensis)","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.20227024","title":"Additional file 9 of Integrated transcriptome and hormonal analysis of naphthalene acetic acid-induced adventitious root formation of tea cuttings (Camellia sinensis)","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.26750603","title":"Additional file 19 of Metabolomics and transcriptomics combined with physiology reveal key metabolic pathway responses in tobacco roots exposed to NaHS","publisher":"figshare","resource_type":"Dataset"},{"doi":"10.6084/m9.figshare.26750606.v1","title":"Additional file 20 of Metabolomics and transcriptomics combined with physiology reveal key metabolic pathway responses in tobacco roots exposed to NaHS","publisher":"figshare","resource_type":"Dataset"},{"doi":"10.6084/m9.figshare.26750600.v1","title":"Additional file 18 of Metabolomics and transcriptomics combined with physiology reveal key metabolic pathway responses in tobacco roots exposed to NaHS","publisher":"figshare","resource_type":"Dataset"},{"doi":"10.6084/m9.figshare.26750600","title":"Additional file 18 of Metabolomics and transcriptomics combined with physiology reveal key metabolic pathway responses in tobacco roots exposed to NaHS","publisher":"figshare","resource_type":"Dataset"},{"doi":"10.6084/m9.figshare.26750603.v1","title":"Additional file 19 of Metabolomics and transcriptomics combined with physiology reveal key metabolic pathway responses in tobacco roots exposed to NaHS","publisher":"figshare","resource_type":"Dataset"},{"doi":"10.6084/m9.figshare.26750606","title":"Additional file 20 of Metabolomics and transcriptomics combined with physiology reveal key metabolic pathway responses in tobacco roots exposed to NaHS","publisher":"figshare","resource_type":"Dataset"},{"doi":"10.6084/m9.figshare.26750591","title":"Additional file 15 of Metabolomics and transcriptomics combined with physiology reveal key metabolic pathway responses in tobacco roots exposed to NaHS","publisher":"figshare","resource_type":"Dataset"},{"doi":"10.6084/m9.figshare.26750597.v1","title":"Additional file 17 of Metabolomics and transcriptomics combined with physiology reveal key metabolic pathway responses in tobacco roots exposed to NaHS","publisher":"figshare","resource_type":"Dataset"},{"doi":"10.6084/m9.figshare.26750588","title":"Additional file 14 of Metabolomics and transcriptomics combined with physiology reveal key metabolic pathway responses in tobacco roots exposed to NaHS","publisher":"figshare","resource_type":"Dataset"},{"doi":"10.6084/m9.figshare.26750588.v1","title":"Additional file 14 of Metabolomics and transcriptomics combined with physiology reveal key metabolic pathway responses in tobacco roots exposed to NaHS","publisher":"figshare","resource_type":"Dataset"},{"doi":"10.6084/m9.figshare.26750594","title":"Additional file 16 of Metabolomics and transcriptomics combined with physiology reveal key metabolic pathway responses in tobacco roots exposed to NaHS","publisher":"figshare","resource_type":"Dataset"},{"doi":"10.6084/m9.figshare.26750597","title":"Additional file 17 of Metabolomics and transcriptomics combined with physiology reveal key metabolic pathway responses in tobacco roots exposed to NaHS","publisher":"figshare","resource_type":"Dataset"},{"doi":"10.6084/m9.figshare.26750591.v1","title":"Additional file 15 of Metabolomics and transcriptomics combined with physiology reveal key metabolic pathway responses in tobacco roots exposed to NaHS","publisher":"figshare","resource_type":"Dataset"},{"doi":"10.6084/m9.figshare.26750594.v1","title":"Additional file 16 of Metabolomics and transcriptomics combined with physiology reveal key metabolic pathway responses in tobacco roots exposed to NaHS","publisher":"figshare","resource_type":"Dataset"},{"doi":"10.6084/m9.figshare.26750585.v1","title":"Additional file 13 of Metabolomics and transcriptomics combined with physiology reveal key metabolic pathway responses in tobacco roots exposed to NaHS","publisher":"figshare","resource_type":"Dataset"},{"doi":"10.6084/m9.figshare.26750585","title":"Additional file 13 of Metabolomics and transcriptomics combined with physiology reveal key metabolic pathway responses in tobacco roots exposed to NaHS","publisher":"figshare","resource_type":"Dataset"},{"doi":"10.6084/m9.figshare.26750579.v1","title":"Additional file 11 of Metabolomics and transcriptomics combined with physiology reveal key metabolic pathway responses in tobacco roots exposed to NaHS","publisher":"figshare","resource_type":"Dataset"}],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-06-07T22:30:17.107975Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}