{"doi":"10.1101/2024.11.13.24316383","title":"RF shimming strategy for an open 60-channel RF transmit 7T head coil for routine use on the single transmit mode","abstract":"Abstract Purpose To develop an RF shimming approach for operating the 2 nd Generation Tic Tac Toe RF Coil System (60 transmit channels integrated with 32-channel receive insert) for routine use in 7T neuro MRI on the single transmit mode. Methods RF simulations were performed and used to develop non-subject-specific RF shim cases over three anatomically detailed head models: adult male, adult female, and child female. Multi-ROI shimming strategies were developed and implemented. B 1 + maps and in-vivo images were acquired on the single transmit mode of a 7T scanner using the RF shim cases derived from the computer simulations. Results The availability of 60 transmit channels enables more control over RF power efficiency, SAR efficiency, and B 1 + homogeneity using RF shimming. On the single transmit mode, the 2 nd Generation Tic Tac Toe RF Coil System consistently provides homogeneous B 1 + field distribution with extended coverage into the temporal lobes, cerebellum, reaching all the way to C5-C6. Safe levels of SAR are also achieved. Conclusion By using a non-subject specific RF shimming approach derived from computer simulations, the 2 nd Generation Tic Tac Toe RF Coil System allows for robust, routine neuroimaging (> 1750 in-vivo scanning sessions over the past 28 months) at 7T in single transmit mode.","journal":"medRxiv","year":2024,"id":489283,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9548,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":528816,"name":"Tales Santini","orcid":"0000-0003-4533-9190","position":1,"is_corresponding":false},{"id":1295596,"name":"Anthony DeFranco","orcid":"0000-0002-7938-163X","position":2,"is_corresponding":false},{"id":1316726,"name":"Jacob Berardinelli","orcid":"0009-0007-3428-4821","position":3,"is_corresponding":false},{"id":804119,"name":"Hecheng Jin","orcid":"0000-0002-9855-2481","position":4,"is_corresponding":false},{"id":1334188,"name":"Jinghang Li","orcid":"0000-0002-0898-0897","position":5,"is_corresponding":false},{"id":1068265,"name":"Cong Chu","orcid":null,"position":6,"is_corresponding":false},{"id":1334635,"name":"Jeremy Berardo","orcid":null,"position":7,"is_corresponding":false},{"id":528819,"name":"Tamer S. Ibrahim","orcid":"0000-0001-6738-5855","position":8,"is_corresponding":false},{"id":1275918,"name":"Andrea Sajewski","orcid":"0000-0002-5978-268X","position":0,"is_corresponding":true}],"reference_count":27,"raw_metadata":null,"created_at":"2026-07-19T02:08:23.929823Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}