{"doi":"10.1101/2024.06.16.599236","title":"Densely sampled stimulus-response map of human cortex with single pulse TMS-EEG and its relation to whole brain neuroimaging measures","abstract":"Large-scale networks underpin brain functions. How such networks respond to focal stimulation can help decipher complex brain processes and optimize brain stimulation treatments. To map such stimulation-response patterns across the brain non-invasively, we recorded concurrent EEG responses from single-pulse transcranial magnetic stimulation (i.e., TMS-EEG) from over 100 cortical regions with two orthogonal coil orientations from one densely-sampled individual. We also acquired Human Connectome Project (HCP)-styled diffusion imaging scans (six), resting-state functional Magnetic Resonance Imaging (fMRI) scans (120 mins), resting-state EEG scans (108 mins), and structural MR scans (T1- and T2-weighted). Using the TMS-EEG data, we applied network science-based community detection to reveal insights about the brain's causal-functional organization from both a stimulation and recording perspective. We also computed structural and functional maps and the electric field of each TMS stimulation condition. Altogether, we hope the release of this densely sampled (n=1) dataset will be a uniquely valuable resource for both basic and clinical neuroscience research.","journal":"bioRxiv (Cold Spring Harbor Laboratory)","year":2024,"id":487120,"datarank":0.21693295602406612,"base_score":1.3862943611198906,"endowment":1.3862943611198906,"self_citation_contribution":0.20794415416798362,"citation_network_contribution":0.008988801856082508,"self_endowment_contribution":0.20794415416798362,"citer_contribution":0.008988801856082508,"corpus_percentile":36.96913436992342,"corpus_rank":8149,"citation_count":3,"citer_count":3,"citers_with_citation_signal":2,"citers_with_endowment":2,"datacite_reuse_total":0,"is_dataset":true,"is_dataset_confidence":0.6019,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1175609,"name":"Molly V. Lucas","orcid":"0000-0001-7824-2219","position":1,"is_corresponding":false},{"id":344117,"name":"Christopher C. Cline","orcid":"0000-0003-1442-8641","position":2,"is_corresponding":false},{"id":1331482,"name":"Matthew Menezes","orcid":null,"position":3,"is_corresponding":false},{"id":1331115,"name":"Sanggyun Kim","orcid":"0000-0002-0620-3090","position":4,"is_corresponding":false},{"id":1331483,"name":"Faizan Badami","orcid":null,"position":5,"is_corresponding":false},{"id":605648,"name":"Manjari Narayan","orcid":"0000-0001-5348-270X","position":6,"is_corresponding":false},{"id":241391,"name":"Wei Wu","orcid":"0000-0003-3938-8359","position":7,"is_corresponding":false},{"id":294684,"name":"Zafiris J. Daskalakis","orcid":"0000-0001-9502-0538","position":8,"is_corresponding":false},{"id":241405,"name":"Amit Etkin","orcid":"0000-0001-8259-3521","position":9,"is_corresponding":false},{"id":648501,"name":"Manish Saggar","orcid":"0000-0002-5307-2249","position":10,"is_corresponding":false},{"id":931768,"name":"Yinming Sun","orcid":"0000-0001-5353-7029","position":0,"is_corresponding":true}],"reference_count":57,"raw_metadata":null,"created_at":"2026-07-19T02:08:06.013846Z","pmid":"38948696","pmcid":"PMC11212865","fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}