{"doi":"10.1101/2024.02.26.582115","title":"The choice-wide behavioral association study: data-driven identification of interpretable behavioral components","abstract":"Behavior contains rich structure across many timescales, but there is a dearth of methods to identify relevant components, especially over the longer periods required for learning and decision-making. Inspired by the goals and techniques of genome-wide association studies, we present a data-driven method-the choice-wide behavioral association study: CBAS-that systematically identifies such behavioral features. CBAS uses a powerful, resampling-based, method of multiple comparisons correction to identify sequences of actions or choices that either differ significantly between groups or significantly correlate with a covariate of interest. We apply CBAS to different tasks and species (flies, rats, and humans) and find, in all instances, that it provides interpretable information about each behavioral task.","journal":"bioRxiv (Cold Spring Harbor Laboratory)","year":2024,"id":486735,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":3,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9047,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1330872,"name":"Nicole O. Yokota","orcid":null,"position":1,"is_corresponding":false},{"id":461976,"name":"Christina Y. Lee","orcid":"0000-0002-9393-2178","position":2,"is_corresponding":false},{"id":389445,"name":"Cristofer M. Holobetz","orcid":null,"position":3,"is_corresponding":false},{"id":1330873,"name":"Ali Chaudhry","orcid":null,"position":4,"is_corresponding":false},{"id":1330874,"name":"Greer Williams","orcid":null,"position":5,"is_corresponding":false},{"id":1330875,"name":"Jane Ton","orcid":null,"position":6,"is_corresponding":false},{"id":1330876,"name":"Mihika Mehra","orcid":null,"position":7,"is_corresponding":false},{"id":388237,"name":"Viktor Kharazia","orcid":"0000-0003-0642-6080","position":8,"is_corresponding":false},{"id":388241,"name":"Dilworth Y. Parkinson","orcid":"0000-0002-1817-0716","position":9,"is_corresponding":false},{"id":1330501,"name":"Joseph P. Romano","orcid":"0000-0002-9685-8372","position":10,"is_corresponding":false},{"id":23456,"name":"Peter Dayan","orcid":"0000-0003-3476-1839","position":11,"is_corresponding":false},{"id":388036,"name":"David B. Kastner","orcid":"0000-0001-9681-425X","position":0,"is_corresponding":true}],"reference_count":58,"raw_metadata":null,"created_at":"2026-07-19T02:08:01.404471Z","pmid":"38464037","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}