{"doi":"10.1101/2023.09.17.23295681","title":"Sharing and Reusing Computable Phenotype Definitions","abstract":"Background: A scalable approach for the sharing and reuse of human-readable and computer-executable phenotype definitions can facilitate the reuse of electronic health records for cohort identification and research studies. Description: We developed a tool called Sharephe for the Informatics for Integrating Biology and the Bedside (i2b2) platform. Sharephe consists of a plugin for i2b2 and a cloud-based searchable repository of computable phenotypes, has the functionality to import to and export from the repository, and has the ability to link to supporting metadata. Discussion: The i2b2 platform enables researchers to create, evaluate, and implement phenotypes without knowing complex query languages. In an initial evaluation, two sites on the Evolve to Next-Gen ACT (ENACT) network used Sharephe to successfully create, share, and reuse phenotypes. Conclusion: The combination of a cloud-based computable repository and an i2b2 plugin for accessing the repository enables investigators to store and retrieve phenotypes from anywhere and at any time and to collaborate across sites in a research network.","journal":"medRxiv","year":2023,"id":395092,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":3,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.8987,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1169906,"name":"Louisa Yu Zhang","orcid":"0000-0002-2599-6962","position":1,"is_corresponding":false},{"id":576905,"name":"Kevin D. Bui","orcid":"0000-0002-0361-4521","position":2,"is_corresponding":false},{"id":1162341,"name":"Eugene M. Sadhu","orcid":"0000-0001-9155-6730","position":3,"is_corresponding":false},{"id":557178,"name":"Malarkodi Jebathilagam Samayamuthu","orcid":"0000-0003-0061-8196","position":4,"is_corresponding":false},{"id":225292,"name":"Michele Morris","orcid":"0000-0002-3255-5727","position":5,"is_corresponding":false},{"id":225296,"name":"Shyam Visweswaran","orcid":"0000-0002-2079-8684","position":0,"is_corresponding":true}],"reference_count":14,"raw_metadata":null,"created_at":"2026-07-19T01:19:18.686170Z","pmid":"37790390","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}