{"doi":"10.1101/2023.01.04.23284151","title":"Promoting Sleep Duration in the Pediatric Setting Using a Mobile Health Platform: A Randomized Optimization Trial","abstract":"Abstract Objective Determine the optimal combination of digital health intervention component settings that increase average sleep duration by ≥30 minutes per weeknight. Methods Optimization trial using a 2 5 factorial design. The trial included 2 week run-in, 7 week intervention, and 2 week follow-up periods. Typically developing children aged 9-12y, with weeknight sleep duration <8.5 hours were enrolled (N=97). All received sleep monitoring and performance feedback. The five candidate intervention components ( with their settings to which participants were randomized ) were: 1) sleep goal ( guideline-based or personalized ); 2) screen time reduction messaging ( inactive or active ); 3) daily routine establishing messaging ( inactive or active ); 4) child-directed loss-framed financial incentive ( inactive or active ); and 5) caregiver-directed loss-framed financial incentive ( inactive or active ). The primary outcome was weeknight sleep duration (hours per night). The optimization criterion was: ≥30 minutes average increase in sleep duration on weeknights. Results Average baseline sleep duration was 7.7 hours per night. The highest ranked combination included the core intervention plus the following intervention components: sleep goal (either setting was effective), caregiver-directed loss-framed incentive, messaging to reduce screen time, and messaging to establish daily routines. This combination increased weeknight sleep duration by an average of 39.6 (95% CI: 36.0, 43.1) minutes during the intervention period and by 33.2 (95% CI: 28.9, 37.4) minutes during the follow-up period. Conclusions Optimal combinations of digital health intervention component settings were identified that effectively increased weeknight sleep duration. This could be a valuable remote patient monitoring approach to treat insufficient sleep in the pediatric setting.","journal":"medRxiv","year":2023,"id":395604,"datarank":0.16479184330021646,"base_score":1.0986122886681096,"endowment":1.0986122886681096,"self_citation_contribution":0.16479184330021646,"citation_network_contribution":0.0,"self_endowment_contribution":0.16479184330021646,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9449,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":795090,"name":"Adriana Morales","orcid":"0000-0002-6721-2257","position":1,"is_corresponding":false},{"id":320982,"name":"Ariel A. Williamson","orcid":"0000-0003-3008-3065","position":2,"is_corresponding":false},{"id":572993,"name":"Abigail Jawahar","orcid":null,"position":3,"is_corresponding":false},{"id":572994,"name":"Lionola Juste","orcid":null,"position":4,"is_corresponding":false},{"id":453634,"name":"Mary Ellen Vajravelu","orcid":"0000-0002-5839-7923","position":5,"is_corresponding":false},{"id":45189,"name":"Babette S. Zemel","orcid":"0000-0002-6164-7348","position":6,"is_corresponding":false},{"id":301393,"name":"David F. Dinges","orcid":"0000-0003-2151-4492","position":7,"is_corresponding":false},{"id":572159,"name":"Alexander G. Fiks","orcid":"0000-0001-6525-8764","position":8,"is_corresponding":false},{"id":45175,"name":"Jonathan A. Mitchell","orcid":"0000-0003-3765-2419","position":0,"is_corresponding":true}],"reference_count":48,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-19T01:19:22.857556Z","pmid":"36711634","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}