{"doi":"10.1101/2022.09.25.509388","title":"Feasibility Analyses and Experimental Confirmation of Dove Prism Based Dual-fiberscope Rotary Joint","abstract":"Abstract Two-photon fluorescence microscopy has enjoyed its wide adoption in neuroscience. Head-mounted miniaturized fiberscopes offered an exciting opportunity for enabling neural imaging in freely-behaving animals with high 3D resolution. Here we propose a dual-fiberscope rotary joint based on a Dove prism, for enabling simultaneous two-photon imaging of two brain regions with two fiberscopes in freely-walking/rotating mice. Analytic proof has confirmed the key properties of a Dove prism. Feasibility analyses and proof-of-concept experimental results have demonstrated the feasibility of such a rotary joint for allowing two fiberscopes to rotate simultaneously while maintaining an excellent single-mode fiber-to-fiber coupling for the excitation femtosecond laser. Fiberscopes with a dual-probe rotary joint offer an exciting opportunity to explore neural network dynamics of multiple interconnected brain regions in freely-walking rotating animals.","journal":"bioRxiv (Cold Spring Harbor Laboratory)","year":2022,"id":311596,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9512,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":394110,"name":"Hyeon‐Cheol Park","orcid":null,"position":1,"is_corresponding":false},{"id":1007749,"name":"Haolin Zhang","orcid":"0000-0002-6470-4272","position":2,"is_corresponding":false},{"id":295612,"name":"Xingde Li","orcid":"0000-0002-4725-3297","position":3,"is_corresponding":false},{"id":1007748,"name":"Yuehan Liu","orcid":"0000-0002-8751-448X","position":0,"is_corresponding":true}],"reference_count":21,"raw_metadata":null,"created_at":"2026-07-19T00:33:28.480200Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}