{"doi":"10.1101/2022.07.15.500187","title":"Illuminating the Druggable Genome through Patent Bioactivity Data","abstract":"Abstract The patent literature is a potentially valuable source of bioactivity data. The SureChEMBL database ( https://www.surechembl.org/ ) is a publicly available large-scale resource that contains compounds extracted on a daily basis from the full text, images and attachments of patent documents, through an automated text and image-mining pipeline. In this paper we describe a process to prioritise 3.7 million life science relevant patents obtained from SureChEMBL, according to how likely they were to contain bioactivity data for potent small molecules on less-studied targets, according to the classification developed by the Illuminating the Druggable Genome (IDG) project. The overall goal was to select a smaller number of patents that could be manually curated and incorporated into the ChEMBL database. We describe the approach taken, the results obtained, and provide some illustrative examples.","journal":"bioRxiv (Cold Spring Harbor Laboratory)","year":2022,"id":301559,"datarank":0.2257881039292769,"base_score":1.0986122886681096,"endowment":1.0986122886681096,"self_citation_contribution":0.16479184330021646,"citation_network_contribution":0.06099626062906043,"self_endowment_contribution":0.16479184330021646,"citer_contribution":0.06099626062906043,"corpus_percentile":37.82006652742322,"corpus_rank":8039,"citation_count":2,"citer_count":2,"citers_with_citation_signal":2,"citers_with_endowment":2,"datacite_reuse_total":0,"is_dataset":true,"is_dataset_confidence":0.9169,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":75386,"name":"Anna Gaulton","orcid":"0000-0003-2634-7400","position":1,"is_corresponding":false},{"id":75390,"name":"Eloy Félix","orcid":"0000-0002-5512-6810","position":2,"is_corresponding":false},{"id":992672,"name":"Tevfik Kizilören","orcid":"0000-0001-8129-6488","position":3,"is_corresponding":false},{"id":24384,"name":"Ricardo Arcila","orcid":"0000-0002-8253-7375","position":4,"is_corresponding":false},{"id":68160,"name":"Tudor I. Oprea","orcid":"0000-0002-6195-6976","position":5,"is_corresponding":false},{"id":75404,"name":"Andrew R. Leach","orcid":"0000-0001-8178-0253","position":6,"is_corresponding":false},{"id":75391,"name":"María Paula Magariños","orcid":"0000-0003-2769-4105","position":0,"is_corresponding":true}],"reference_count":33,"raw_metadata":null,"created_at":"2026-07-19T00:32:02.193874Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}