{"doi":"10.1101/2020.06.11.147330","title":"Right lateralized posterior parietal theta-gamma coupling during sustained attention in mice","abstract":"Abstract Sustained attention is supported by circuits in the frontoparietal attention network. In human and primate studies, the right posterior parietal cortex (PPC) shows dominance for sustained attention, and phase-amplitude coupling (PAC) throughout the frontoparietal network correlates with performance on attention tasks. Here we evaluate oscillatory dynamics of bilateral PPC in mice during the 5-Choice Serial Reaction Time Task (5-CSRTT). Right PPC theta-gamma PAC (TG-PAC) and gamma power were independently elevated to a greater degree than the left PPC during the period prior to a correct response and were significantly correlated with accuracy in both simple and difficult tasks. Greater task difficulty was also associated with greater hemispheric asymmetry in TG-PAC, favoring the right PPC. These findings highlight the engagement of PPC with sustained attention in mice, reflected by increases in TG-PAC and gamma power, with maximal expression in the right hemisphere.","journal":"bioRxiv (Cold Spring Harbor Laboratory)","year":2020,"id":126910,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9487,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":574939,"name":"Corrinne Dunbar","orcid":"0000-0002-3895-1966","position":1,"is_corresponding":false},{"id":575407,"name":"Alina Sonesra","orcid":null,"position":2,"is_corresponding":false},{"id":574940,"name":"Suhyeorn Park","orcid":"0000-0003-1525-0638","position":3,"is_corresponding":false},{"id":574941,"name":"Timothy Pham","orcid":"0009-0000-4526-6353","position":4,"is_corresponding":false},{"id":371107,"name":"Rodney C. Samaco","orcid":"0000-0001-5636-5314","position":5,"is_corresponding":false},{"id":237689,"name":"Brett L. Foster","orcid":"0000-0002-2621-5574","position":6,"is_corresponding":false},{"id":366241,"name":"Atul Maheshwari","orcid":"0000-0003-3045-7901","position":7,"is_corresponding":false},{"id":575406,"name":"Ryan Yang","orcid":null,"position":0,"is_corresponding":true}],"reference_count":53,"raw_metadata":null,"created_at":"2026-07-18T23:15:27.226519Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}