{"doi":"10.1101/2020.02.13.945485","title":"Identification of 2019-nCoV related coronaviruses in Malayan pangolins in southern China","abstract":"Abstract The ongoing outbreak of viral pneumonia in China and beyond is associated with a novel coronavirus, provisionally termed 2019-nCoV. This outbreak has been tentatively associated with a seafood market in Wuhan, China, where the sale of wild animals may be the source of zoonotic infection. Although bats are likely reservoir hosts for 2019-nCoV, the identity of any intermediate host facilitating transfer to humans is unknown. Here, we report the identification of 2019-nCoV related coronaviruses in pangolins ( Manis javanica ) seized in anti-smuggling operations in southern China. Metagenomic sequencing identified pangolin associated CoVs that belong to two sub-lineages of 2019-nCoV related coronaviruses, including one very closely related to 2019-nCoV in the receptor-binding domain. The discovery of multiple lineages of pangolin coronavirus and their similarity to 2019-nCoV suggests that pangolins should be considered as possible intermediate hosts for this novel human virus and should be removed from wet markets to prevent zoonotic transmission.","journal":"The Sydney eScholarship Repository (The University of Sydney)","year":2020,"id":118319,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":116,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9482,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":104798,"name":"Marcus Ho-Hin Shum","orcid":null,"position":1,"is_corresponding":false},{"id":104800,"name":"Huachen Zhu","orcid":"0000-0003-2711-0501","position":2,"is_corresponding":false},{"id":104801,"name":"Yigang Tong","orcid":"0000-0002-8503-8045","position":3,"is_corresponding":false},{"id":104803,"name":"Xue-Bing Ni","orcid":"0000-0002-5542-8165","position":4,"is_corresponding":false},{"id":104804,"name":"Yunshi Liao","orcid":null,"position":5,"is_corresponding":false},{"id":104807,"name":"Wei Wei","orcid":"0009-0000-6345-5369","position":6,"is_corresponding":false},{"id":104814,"name":"Y. M. Cheung","orcid":"0000-0003-0053-3969","position":7,"is_corresponding":false},{"id":296041,"name":"Wenjuan Li","orcid":"0000-0002-2231-7338","position":8,"is_corresponding":false},{"id":104815,"name":"Lian‐Feng Li","orcid":"0000-0001-9653-5533","position":9,"is_corresponding":false},{"id":32569,"name":"GM Leung","orcid":"0000-0002-2503-6283","position":10,"is_corresponding":false},{"id":39971,"name":"Edward C. Holmes","orcid":"0000-0001-9596-3552","position":11,"is_corresponding":false},{"id":104819,"name":"Yanling Hu","orcid":"0000-0002-0477-026X","position":12,"is_corresponding":false},{"id":104820,"name":"Yi Guan","orcid":"0000-0001-6057-9243","position":13,"is_corresponding":false},{"id":32568,"name":"Tommy Tsan‐Yuk Lam","orcid":"0000-0002-9769-1527","position":0,"is_corresponding":true}],"reference_count":21,"raw_metadata":null,"created_at":"2026-07-18T23:13:58.531532Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}