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CrispRVariants-enabled analyses of newly generated and existing genome editing datasets underscore how careful consideration of the full variant spectrum gives insight toward effective guide and amplicon design as well as the mutagenic process.</jats:p>","journal":null,"year":null,"id":642904,"datarank":0.20794415416798362,"base_score":1.3862943611198906,"endowment":1.3862943611198906,"self_citation_contribution":0.20794415416798362,"citation_network_contribution":0.0,"self_endowment_contribution":0.20794415416798362,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":3,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":994368,"name":"Alexa Burger","orcid":"0000-0001-7137-3910","position":1,"is_corresponding":false},{"id":1672499,"name":"Berthin Biyong","orcid":null,"position":2,"is_corresponding":false},{"id":994365,"name":"Anastasia Felker","orcid":"0000-0002-3734-2026","position":3,"is_corresponding":false},{"id":1672501,"name":"Christopher Hess","orcid":null,"position":4,"is_corresponding":false},{"id":1171510,"name":"Elena Chiavacci","orcid":"0000-0003-3924-3635","position":5,"is_corresponding":false},{"id":1672503,"name":"Jonas Zaugg","orcid":null,"position":6,"is_corresponding":false},{"id":1672504,"name":"Carolin Anders","orcid":null,"position":7,"is_corresponding":false},{"id":1672505,"name":"Martin Jinek","orcid":null,"position":8,"is_corresponding":false},{"id":652950,"name":"Christian Mosimann","orcid":"0000-0002-0749-2576","position":9,"is_corresponding":false},{"id":32458,"name":"Mark D. 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CrispRVariants-enabled analyses of newly generated and existing genome editing datasets underscore how careful consideration of the full variant spectrum gives insight toward effective guide and amplicon design as well as the mutagenic process.</jats:p>","is_dataset_classified":null,"base_score":1.3862943611198906,"endowment":1.3862943611198906,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"19767382","pmcid":null,"openalex_id":"https://openalex.org/W2327267654","authors":[],"funders":[{"funder_name":"European Commission","grant_id":"305626","title":"Rapid development and distribution of statistical tools for high-throughput sequencing data"}],"total_grants":1,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[{"year":2016,"count":2},{"year":2021,"count":1}],"oa_status":"green","license":"cc-by-nd","oa_locations":[{"url":"https://www.biorxiv.org/content/biorxiv/early/2016/03/10/034140.full.pdf","host_type":"repository"},{"url":"https://www.biorxiv.org/content/biorxiv/early/2016/03/10/034140.full.pdf","host_type":"repository"},{"url":"https://syndication.highwire.org/content/doi/10.1101/034140","host_type":"publisher"},{"url":"https://doi.org/10.1101/034140","host_type":"repository"},{"url":"https://dx.doi.org/10.1101/034140","host_type":""},{"url":"http://dx.doi.org/10.1101/034140","host_type":""}],"fields_of_study":["CRISPR and Genetic Engineering","Evolution and Genetic Dynamics","Plant Virus Research Studies","0301 basic medicine","03 medical and health sciences","0206 medical engineering","02 engineering and technology"],"mesh_terms":[],"keywords":["Genome editing","CRISPR","Cas9","Computational biology","Endonuclease","Mutagenesis","Computer science","Genome engineering","Genome","Amplicon","Genetics","Biology","Mutation","DNA","Gene","Polymerase chain reaction"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-08T10:42:42.036686Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}