{"doi":"10.1098/rstb.1975.0053","title":"The effect of hyaluronic acid on proteoglycan synthesis and secretion by chondrocytes of adult cartilage","abstract":"<jats:title>Abstract</jats:title>\n                  <jats:p>The chondrocyte is a specialized cell that synthesizes proteoglycans of a type found only in cartilage and nucleus pulposus. These proteoglycans are distinct in forming multiple aggregates of unique structure in which hyaluronic acid provides a central chain to which many proteoglycan molecules are bound at one end only.</jats:p>","journal":"Philosophical Transactions of the Royal Society of London. B, Biological Sciences","year":1975,"id":658139,"datarank":3.6578590774936934,"base_score":3.6888794541139363,"endowment":3.6888794541139363,"self_citation_contribution":0.5533319181170905,"citation_network_contribution":3.104527159376603,"self_endowment_contribution":0.5533319181170905,"citer_contribution":3.104527159376603,"corpus_percentile":null,"corpus_rank":null,"citation_count":39,"citer_count":37,"citers_with_citation_signal":35,"citers_with_endowment":35,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1718036,"name":"Helen Muir","orcid":null,"position":1,"is_corresponding":false},{"id":1718035,"name":"O. W. Weibkin","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"The effect of hyaluronic acid on proteoglycan synthesis and secretion by chondrocytes of adult cartilage","abstract":"<jats:title>Abstract</jats:title>\n                  <jats:p>The chondrocyte is a specialized cell that synthesizes proteoglycans of a type found only in cartilage and nucleus pulposus. These proteoglycans are distinct in forming multiple aggregates of unique structure in which hyaluronic acid provides a central chain to which many proteoglycan molecules are bound at one end only.</jats:p>","is_dataset_classified":null,"base_score":3.6888794541139363,"endowment":3.6888794541139363,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"239423","pmcid":null,"openalex_id":"https://openalex.org/W1981369290","authors":[],"funders":[],"total_grants":0,"fwci":1.7613,"citation_percentile":0.83570959,"influential_citations":0,"citation_trend":[{"year":2014,"count":1},{"year":2024,"count":1}],"oa_status":"closed","license":"https://royalsociety.org/journals/ethics-policies/data-sharing-mining/","oa_locations":[{"url":"https://royalsocietypublishing.org/doi/pdf/10.1098/rstb.1975.0053","host_type":"publisher"},{"url":"https://royalsocietypublishing.org/rstb/article-pdf/271/912/283/334986/rstb.1975.0053.pdf","host_type":"publisher"},{"url":"https://doi.org/10.1098/rstb.1975.0053","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/239423","host_type":"repository"}],"fields_of_study":["Proteoglycans and glycosaminoglycans research","Osteoarthritis Treatment and Mechanisms","Glycosylation and Glycoproteins Research","Animals","Cartilage","Cells, Cultured","Chondroitin","Chromatography, Gel","Depression, Chemical","Extracellular Space","Glycosaminoglycans","Hyaluronic Acid","Microscopy, Electron","Oligosaccharides","Proteoglycans","Structure-Activity Relationship","Sulfates","Swine","Trypsin"],"mesh_terms":["Animals","Cartilage","Cells, Cultured","Chondroitin","Chromatography, Gel","Depression, Chemical","Extracellular Space","Glycosaminoglycans","Hyaluronic Acid","Microscopy, Electron","Oligosaccharides","Proteoglycans","Structure-Activity Relationship","Sulfates","Swine","Trypsin"],"keywords":["Hyaluronic acid","Proteoglycan","Chemistry","Cartilage","Chondrocyte","Secretion","Biochemistry","Cell biology","Glycosaminoglycan","Extracellular matrix","In vitro","Anatomy","Biology"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-12T03:24:14.181543Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}