{"doi":"10.1098/rsos.250132","title":"Translational reprogramming under heat stress: a plant’s perspective","abstract":"<jats:p>\n                    Plants experience dynamic and sometimes extreme fluctuations in temperature on hourly, daily and seasonal scales, which are becoming increasingly challenging as climate change progresses. To maximize fitness and chances of survival, plants continuously adjust their growth, development and physiology to their temperature environment. Changes in protein synthesis are central to these acclimatization processes, enabling rapid and precise modulation of cellular functions. In this review, we discuss the molecular mechanisms driving heat-induced translational reprogramming, integrating insights from animal and yeast systems with current knowledge and emerging hypotheses in plants. We revisit the core stages of translation—initiation, elongation and termination—and the roles of associated translation factors while also exploring emerging areas of interest, including biomolecular condensates, RNA modifications and\n                    <jats:italic toggle=\"yes\">cis</jats:italic>\n                    -regulatory elements. Finally, we consider how a deeper understanding of translational control could be harnessed to enhance crop resilience in the face of climate change.\n                  </jats:p>","journal":"Royal Society Open Science","year":2025,"id":649785,"datarank":0.20794415416798362,"base_score":1.3862943611198906,"endowment":1.3862943611198906,"self_citation_contribution":0.20794415416798362,"citation_network_contribution":0.0,"self_endowment_contribution":0.20794415416798362,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":3,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1694046,"name":"Aminin Taqrir Akramin","orcid":"0009-0002-5450-0046","position":1,"is_corresponding":false},{"id":1694048,"name":"Martin Balcerowicz","orcid":"0000-0001-9462-4436","position":2,"is_corresponding":false},{"id":1694045,"name":"Moray Smith","orcid":"0000-0001-9363-3170","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Translational reprogramming under heat stress: a plant’s perspective","abstract":"<jats:p>\n                    Plants experience dynamic and sometimes extreme fluctuations in temperature on hourly, daily and seasonal scales, which are becoming increasingly challenging as climate change progresses. To maximize fitness and chances of survival, plants continuously adjust their growth, development and physiology to their temperature environment. Changes in protein synthesis are central to these acclimatization processes, enabling rapid and precise modulation of cellular functions. In this review, we discuss the molecular mechanisms driving heat-induced translational reprogramming, integrating insights from animal and yeast systems with current knowledge and emerging hypotheses in plants. We revisit the core stages of translation—initiation, elongation and termination—and the roles of associated translation factors while also exploring emerging areas of interest, including biomolecular condensates, RNA modifications and\n                    <jats:italic toggle=\"yes\">cis</jats:italic>\n                    -regulatory elements. Finally, we consider how a deeper understanding of translational control could be harnessed to enhance crop resilience in the face of climate change.\n                  </jats:p>","is_dataset_classified":null,"base_score":1.3862943611198906,"endowment":1.3862943611198906,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"40727411","pmcid":"PMC12303099","openalex_id":"https://openalex.org/W4412438408","authors":[],"funders":[{"funder_name":"Biotechnology and Biological Sciences Research Council","grant_id":"BB/Y001672/1","title":"Unravelling post-transcriptional mechanisms governing the plant's response to high temperature"},{"funder_name":"Biotechnology and Biological Sciences Research Council","grant_id":"","title":null},{"funder_name":"Royal Society","grant_id":"","title":null}],"total_grants":3,"fwci":1.2189,"citation_percentile":0.7836113,"influential_citations":0,"citation_trend":[{"year":2025,"count":1},{"year":2026,"count":2}],"oa_status":"gold","license":"cc-by","oa_locations":[{"url":"https://doi.org/10.1098/rsos.250132","host_type":"journal"},{"url":"https://doi.org/10.1098/rsos.250132","host_type":"publisher"},{"url":"https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.250132","host_type":"publisher"},{"url":"https://royalsocietypublishing.org/doi/full-xml/10.1098/rsos.250132","host_type":"publisher"},{"url":"https://pubmed.ncbi.nlm.nih.gov/40727411","host_type":"repository"},{"url":"https://discovery.dundee.ac.uk/en/publications/bf7fd871-de01-4e08-a37f-9165e734e4fa","host_type":"repository"},{"url":"https://doaj.org/article/a3c2cf7201084556bf85c6e008cc6f42","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12303099","host_type":"repository"},{"url":"https://discovery.dundee.ac.uk/ws/files/156204859/smith-et-al-2025-translational-reprogramming-under-heat-stress-a-plant-s-perspective.pdf","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC12303099","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC12303099?pdf=render","host_type":"Europe_PMC"},{"url":"http://dx.doi.org/10.1098/rsos.250132","host_type":""}],"fields_of_study":["RNA and protein synthesis mechanisms","RNA modifications and cancer","RNA Research and Splicing"],"mesh_terms":[],"keywords":["Reprogramming","Climate change","Biology","Heat stress","Translation (biology)","Psychological resilience","Computational biology","Perspective (graphical)","Computer science","Ecology","Evolutionary biology","Genetics","Psychology","Artificial intelligence","Translation","Protein synthesis","Temperature Sensing","Translation Factors","Science","Q","Biochemistry, Cellular and Molecular Biology"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Climate action"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-10T04:19:29.233556Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}