{"doi":"10.1097/qai.0b013e318236f7d2","title":"Early Retention in HIV Care and Viral Load Suppression","abstract":null,"journal":"JAIDS Journal of Acquired Immune Deficiency Syndromes","year":2012,"id":636960,"datarank":0.8124150603306631,"base_score":5.41610040220442,"endowment":5.41610040220442,"self_citation_contribution":0.8124150603306631,"citation_network_contribution":0.0,"self_endowment_contribution":0.8124150603306631,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":224,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":305152,"name":"K. Rivet Amico","orcid":"0000-0002-4458-6934","position":1,"is_corresponding":false},{"id":525399,"name":"Andrew O. Westfall","orcid":"0000-0002-0468-4695","position":2,"is_corresponding":false},{"id":240253,"name":"Heidi M. Crane","orcid":"0000-0002-3308-7005","position":3,"is_corresponding":false},{"id":546920,"name":"Anne Zinski","orcid":"0000-0003-0414-248X","position":4,"is_corresponding":false},{"id":340157,"name":"James H. Willig","orcid":"0000-0001-7462-368X","position":5,"is_corresponding":false},{"id":311287,"name":"Julia C. Dombrowski","orcid":"0000-0003-1907-9428","position":6,"is_corresponding":false},{"id":400899,"name":"Wynne E. Norton","orcid":null,"position":7,"is_corresponding":false},{"id":525175,"name":"James L. Raper","orcid":"0000-0002-3242-4911","position":8,"is_corresponding":false},{"id":340159,"name":"Mari M. Kitahata","orcid":"0000-0002-5410-7175","position":9,"is_corresponding":false},{"id":280974,"name":"Michael S. Saag","orcid":"0000-0002-8866-1043","position":10,"is_corresponding":false},{"id":313570,"name":"Michael J. Mugavero","orcid":"0000-0001-6916-6701","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Early Retention in HIV Care and Viral Load Suppression","abstract":"BACKGROUND: After HIV diagnosis and linkage to care, achieving and sustaining viral load (VL) suppression has implications for patient outcomes and secondary HIV prevention. We evaluated factors associated with expeditious VL suppression and cumulative VL burden among patients establishing outpatient HIV care. METHODS: Patients initiating HIV medical care from January 2007 to October 2010 at the University of Alabama at Birmingham and University of Washington were included. Multivariable Cox proportional hazards and linear regression models were used to evaluate factors associated with time to VL suppression (<50 copies/mL) and cumulative VL burden, respectively. Viremia copy-years, a novel area under the longitudinal VL curve measure, was used to estimate 2-year cumulative VL burden from clinic enrollment. RESULTS: Among 676 patients, 63% achieved VL <50 copies per milliliter in a median 308 days. In multivariable analysis, patients with more time-updated \"no show\" visits experienced delayed VL suppression (hazard ratio = 0.84 per \"no show\" visit, 95% confidence interval = 0.76 to 0.92). In multivariable linear regression, visit nonadherence was independently associated with greater cumulative VL burden (log(10) viremia copy-years) during the first 2 years in care (Beta coefficient = 0.11 per 10% visit nonadherence, 95% confidence interval = 0.04 to 0.17). Across increasing visit adherence categories, lower cumulative VL burden was observed (mean ± standard deviation log(10) copy × years/mL); 0%-79% adherence: 4.6 ± 0.8; 80%-99% adherence: 4.3 ± 0.7; and 100% adherence: 4.1 ± 0.7 log(10) copy × years/mL, respectively (P < 0.01). CONCLUSIONS: Higher rates of early retention in HIV care are associated with achieving VL suppression and lower cumulative VL burden. These findings are germane for a test and treat approach to HIV prevention.","is_dataset_classified":null,"base_score":5.41610040220442,"endowment":5.41610040220442,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"21937921","pmcid":"PMC3237801","openalex_id":"https://openalex.org/W2042684539","authors":[],"funders":[{"funder_name":"NIMH NIH HHS","grant_id":"L30 MH095060","title":null},{"funder_name":"NIAID NIH HHS","grant_id":"P30AI27767","title":null},{"funder_name":"NIAID NIH HHS","grant_id":"T32 AI007140","title":null},{"funder_name":"NIAID NIH HHS","grant_id":"1R24AI067039-04","title":null},{"funder_name":"NIMH NIH HHS","grant_id":"3K23MH082641-02S1","title":null},{"funder_name":"NIAID NIH HHS","grant_id":"1R21AI087360-01","title":null},{"funder_name":"NIMH NIH HHS","grant_id":"K23 MH082641","title":null},{"funder_name":"NIAID NIH HHS","grant_id":"R21 AI087360","title":null},{"funder_name":"NIMH NIH HHS","grant_id":"K23 MH090923","title":null},{"funder_name":"NIAID NIH HHS","grant_id":"P30 AI027767","title":null},{"funder_name":"NIAID NIH HHS","grant_id":"P30 AI027757","title":null},{"funder_name":"NIMH NIH HHS","grant_id":"5K23MH090923-02","title":null},{"funder_name":"NIAID NIH HHS","grant_id":"R24 AI067039","title":null}],"total_grants":13,"fwci":9.7796,"citation_percentile":0.9899985,"influential_citations":0,"citation_trend":[{"year":2012,"count":13},{"year":2013,"count":26},{"year":2014,"count":25},{"year":2015,"count":27},{"year":2016,"count":14},{"year":2017,"count":19},{"year":2018,"count":24},{"year":2019,"count":15},{"year":2020,"count":15},{"year":2021,"count":10},{"year":2022,"count":13},{"year":2023,"count":7},{"year":2024,"count":4},{"year":2025,"count":9},{"year":2026,"count":3}],"oa_status":"closed","license":null,"oa_locations":[{"url":"http://journals.lww.com/00126334-201201010-00013","host_type":"publisher"},{"url":"https://doi.org/10.1097/qai.0b013e318236f7d2","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/21937921","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3237801","host_type":"repository"}],"fields_of_study":["HIV/AIDS Research and Interventions","HIV/AIDS drug development and treatment","HIV Research and Treatment"],"mesh_terms":["Adult","Drug Administration Schedule","Female","Humans","Male","Middle Aged","Time Factors","HIV Infections","Treatment Outcome","CD4 Lymphocyte Count","Anti-HIV Agents","Viral Load"],"keywords":["Medicine","Hazard ratio","Confidence interval","Viral load","Proportional hazards model","Viremia","Cumulative incidence","Internal medicine","Human immunodeficiency virus (HIV)","Immunology","Cohort"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-06T18:03:00.108903Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}