{"doi":"10.1097/ijg.0b013e318259505a","title":"Anterior Segment Changes After Pilocarpine and Laser Iridotomy for Primary Angle-Closure Suspects With Scheimpflug Photography","abstract":null,"journal":"Journal of Glaucoma","year":2013,"id":650772,"datarank":0.519860385419959,"base_score":3.4657359027997265,"endowment":3.4657359027997265,"self_citation_contribution":0.519860385419959,"citation_network_contribution":0.0,"self_endowment_contribution":0.519860385419959,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":31,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1696927,"name":"Mark R. Lesk","orcid":null,"position":1,"is_corresponding":false},{"id":1696928,"name":"Mélissa Nantel-Battista","orcid":null,"position":2,"is_corresponding":false},{"id":1696929,"name":"Paul J. Harasymowycz","orcid":null,"position":3,"is_corresponding":false},{"id":1696925,"name":"Julia C. Talajic","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Anterior Segment Changes After Pilocarpine and Laser Iridotomy for Primary Angle-Closure Suspects With Scheimpflug Photography","abstract":"PURPOSE: To assess changes in Scheimpflug-based measurements of the anterior segment after pilocarpine administration and prophylactic laser peripheral iridotomy in narrow anterior chamber angles. METHODS: Thirty-seven eyes in 37 patients with occludable angles were included in this prospective interventional case series. Primary angle-closure suspects (iridotrabecular contact in 3 quadrants or more) were enrolled. Patient evaluation included indentation gonioscopy, Goldmann tonometry, and optic nerve examination. The mean of 3 consecutive Pentacam measurements was taken at baseline, 45 minutes after 2% pilocarpine administration, and 1 month after laser peripheral iridotomy (LPI). Anterior chamber angle (ACA), anterior chamber volume (ACV), anterior chamber depth (ACD), pupil diameter, central corneal thickness, and intraocular pressure were measured. RESULTS: ACV increased significantly after LPI (from a mean ± standard error of 94.6 ± 3.6 mm(3) to 108.8 ± 3.4 mm(3), P<0.001), as did the ACA (26.7 ± 0.9 degrees to 28.2 ± 0.8 degrees, P<0.001). Central corneal thickness decreased significantly after LPI (558.1 ± 5.3 μm to 552.6 ± 5.7 μm, P=0.018). Central ACD increased slightly after LPI, but this was not statistically significant (2.13 ± 0.05 mm to 2.15 ± 0.05 mm, P=0.109). Pupil diameter and intraocular pressure also did not change significantly after LPI. After pilocarpine, the ACV decreased significantly (by 4.3 ± 1.3 mm(3), P=0.009), as did the central ACD (by 0.1 ±0.02 mm, P<0.001) and the pupil diameter (by 0.74 ± 0.06 mm, P<0.001). CONCLUSIONS: Scheimpflug photography demonstrates significant anterior segment changes after pilocarpine and after LPI in primary angle-closure suspects.","is_dataset_classified":null,"base_score":3.4657359027997265,"endowment":3.4657359027997265,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"22668977","pmcid":null,"openalex_id":"https://openalex.org/W1998086543","authors":[],"funders":[],"total_grants":0,"fwci":2.063,"citation_percentile":0.86264066,"influential_citations":0,"citation_trend":[{"year":2013,"count":3},{"year":2014,"count":2},{"year":2015,"count":3},{"year":2016,"count":5},{"year":2017,"count":2},{"year":2018,"count":5},{"year":2019,"count":2},{"year":2020,"count":2},{"year":2021,"count":2},{"year":2022,"count":2},{"year":2023,"count":2},{"year":2024,"count":1}],"oa_status":"closed","license":null,"oa_locations":[{"url":"https://journals.lww.com/10.1097/IJG.0b013e318259505a","host_type":"publisher"},{"url":"https://doi.org/10.1097/ijg.0b013e318259505a","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/22668977","host_type":"repository"}],"fields_of_study":["Glaucoma and retinal disorders","Retinal and Macular Surgery","Intraocular Surgery and Lenses"],"mesh_terms":["Aged","Anterior Eye Segment","Female","Gonioscopy","Humans","Intraocular Pressure","Iris","Male","Miotics","Photography","Pilocarpine","Prospective Studies","Pupil","Tonometry, Ocular","Glaucoma, Angle-Closure","Iridectomy","Laser Therapy","Lasers, Solid-State"],"keywords":["Scheimpflug principle","Medicine","Pilocarpine","Ophthalmology","Intraocular pressure","Anterior chamber angle","Gonioscopy","Iridectomy","Pupil","Glaucoma","Tropicamide","Cornea","Optics"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-10T06:04:44.433700Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}